Human ankle-foot gait is the result of a complex interaction between nerves and muscles. A significant number of prosthetic ankles-foots (passive, semi-active, active) have been designed to restore an identical function of a real limb. Excluding passive and semi-active prosthesis, that cannot generate any positive work, one of the biggest challenges in creating these prostheses is providing the needed power and energy during movement. Supplying this power and energy, requires a high-torque and high-power actuator having high weight, thereby causing a dramatic increase in the weight and size of the resulted prosthesis. In this paper, a combination of an active actuator (an electrical motor) and a passive stimulus (a spring) is utilized, which can decrease the needed power and energy. This design does not only support walking mode, but also provides running mode up to 2. 5m/s. Accordingly, the first stage of this article includes mechanical modeling of the ankle and evaluation of efficiency and power consumption in all presented models. Then, a combination of spring and series actuator is selected as the best and optimal combination, which is different from the previous structures. In this structure, power and energy consumption are dramatically reduced up to 58% and 26% in walking mode and 64% and 57% in running mode. Consequently, a lighter motor and battery can supply the required power, so the prosthesis’ s weight is decreased. Thus, in order to optimize power and energy consumption, it is necessary to determine the optimal spring stiffness based on design priorities (maximum power reduction). In the last step, the most suitable segments are developed for receiving the best performance, and then the designed prosthetic ankle is built. The results of simulations and experimental tests show that the produced prosthesis has all the desired performance, and it uses less energy and power while its user is moving.