Background & Purpose: This study aims to propose a model of quality outcomes of work life with a meta-analysis approach and interpretive structural modeling (ISM). Methodology: This is an applied descriptive-quantitative study, in which the quality outcomes of work life were first identified and extracted from 41 papers, published in scientific research papers from 2011 to fall 2019, with a meta-analysis approach. In the next step, the ISM technique was employed to rank these outcomes based on the opinions of 12 faculty members of the Shahid Sattari University of Aeronautical Engineering by determining the model of their relationships. Findings: According to the meta-analysis results, the greatest effect sizes came from organizational performance (0. 745), human resources productivity (0. 707), occupational attachment (0. 683), psychological empowerment (0. 614), organizational entrepreneurship (0. 608), and employee self-efficacy (0. 586), respectively, out of the quality outcomes of work life. Conclusion: Based on the ISM results, the quality outcomes of work life were ranked at four levels. In fact, psychological empowerment had the greatest effectiveness, whereas organizational performance was affected the most.