Pars Journal of Medical Sciences
Year:2020 | Volume:18 | Issue:1|Papers Count:8

Introduction: In order to control Hypertension, it is necessary to understand the methods of blood pressure measurement. Definition and methods of blood pressure measurement have changed in the American guideline based on SPRINT trial (Systolic Blood Pressure Intervention Trial), though Europeans still insist on the standard method of office blood pressure measurement. The differences made by SPRINT method are not fully understood yet. This article compares the measurements done by mercury sphygmomanometers and digital devices, and also evaluates the effect of applying the SPRINT method on these readings. Materials and Methods: 87 patients were enrolled in this study, for all of whom blood pressure was measured in a quiet room after 5 minutes of resting for 3 times (using an automated device for the first 2 times and a mercury sphygmomanometer for the third time). The mean of them was considered as SPRINT like blood pressure. The results were compared to the measurements done by a cardiologist and a nurse using an automated device at the same visit. Result: Office based SBPs were about 8. 47 mmHg higher than SPRINT like measurements (p<0. 001). Diastolic blood pressures were about 7. 05 mmHg higher in office (p<0. 001). Conclusion: Methods employed to measure the blood pressure level have a pivotal effect on the results affecting the final classification and treatment approach.

Introduction: The metabolism of many fats, including free fatty acids and oxidized low density lipoprotein (ox-LDL) play an important role in the development of atherosclerosis. The aim of this study was to determine the association between circulating ox-LDL and acute myocardial infarction. Materials and Methods: The case control study conducted on 43 patients with acute myocardial infarction and 43 volunteers who had no signs, symptoms or history of cardiovascular or cerebrovascular disease and matched to patients for age and sex (control). We used ELISA kit (company of Mercodia, Sweden) to measure circulating ox-LDL. The data recorded and then analyzed by SPSS software version 16. Statistical significance was considered as p-value less than 0. 05. Results: Two study groups significantly were no differences as age, sex, smoking, family history of ischemic heart disease, hypertriglyceridemia, hypercholesterolemia, hypertension, diabetes mellitus type 2, and disease existence. There was a significant difference between the mean concentration of ox-LDL in AMI and control group as it was higher in the patients (2. 14 ± 1. 67 µ g/ml) than the controls (1. 03 ± 1. 18 µ g/ml, p= 0. 001). Using logistic regression analysis and entering variables of study in the model, ox-LDL factor was independently associated with the risk of myocardial infarction (OR= 1. 74, CI95%: 1. 23-2. 45, P= 0. 002). Conclusions: Elevated ox-LDL is associated with the acute myocardial infarction and may also be helpful in the early detection of myocardial infarction.

Introduction: Pain is an unpleasant feeling that usually occurs as a result of tissue injuries. Orchid could have significant analgesic effects in acute and chronic pain modalities due to its glucomannan content. Considering the antioxidant and anti-inflammatory properties of the Orchid root’ s compounds, the aim of this study was to determine the effect of Orchid root extract on the reduction and prevention of formalin-induced pain. Materials and Methods: In this experimental study, 56 male Wistar rats were randomly divided into 7 groups, including Control, Sham (distilled water), Ibuprofen (6 mg/kg) groups and four groups receiving the aqueous extract of Orchid root (80, 160, 320 and 640 mg/kg). All treatments were injected intra peritoneal. Formalin test was performed 30 minutes after injection of Orchid extract. Data were analyzed by one-way ANOVA and Duncan's post-test at a significance level of 0. 05. Results: Orchid at concentrations of 320 and 640 mg/kg caused a significant reduction in acute pain and at concentrations of 160, 320 and 640 mg/kg significantly decreased chronic pain. Ibuprofen also reduced acute and chronic pain induced by formalin. Conclusion: This research demonstrated the dose-dependent anti-nociceptive effect of Orchid root extract which is probably related to glucomannan and its antioxidant and anti-inflammatory properties.

Introduction: A successful cardio-pulmonary resuscitation (CPR) depends on a variety of reasons such as age, sex, patient, the cause of cardio-pulmonary arrest, the time of the start of CPR, etc. This study aimed at investigating the status of cardio-pulmonary resuscitation (CPR) and the related factors thereof in Shahid Motahari Hospital of Marvdasht. Material & Methods: In the present descriptive cross-sectional study all cardio-pulmonary resuscitation (CPR) cases in all medical wards were examined within one year from March-April 2014 through March-April 2015. In this study, all factor related to the cardio-pulmonary resuscitation (CPR) were examined including age, sex, underlying disease, the cause of cardio-pulmonary arrest, the time of start of CPR, existence or lack of the related equipment, presence or absence of the specialist or general physician, the result of CPR, and the side effects thereof. Data were analyzed using descriptive and inferential tests. Results: Totally, CPR performed on 234 patients that 63. 7% and 76. 1% of them were women and aged 40 or older, respectively. 48. 7 % of the CPR operations were successful. There is a significant relationship between the age (p= 0. 012) and sex (p= 0. 001) of the patients and the amount of the success of the CPR. CPR is more successful in patients aged less than 20 years and in women than that of in other age groups and men, respectively. Conclusion: The number of successful CPR operations in Marvdasht Hospital is more than the number of successful CPR in other similar studies. Therefore, it is suggested that planning better and considering the results of this research will be of help in increasing the amount of success in CPR operations.

Introduction: Pregnancy toxemia causes many pregnant mothers at risk for adverse midwifery complications and sometimes the risk of death. If this complication occurs early in the second trimester of pregnancy, the mother will be deprived of having a child as a result of this complicated pregnancy. Here we present a woman who has had premature pregnancy toxsemia. The known risk factors in this woman were not positive.

Introduction: Chronic Pain Refers To Persistent And Long-Lasting Pain That Extends Beyond Normal Range And Over 6 Months. The Most Commonly Used Therapies, Such As Analgesia, Have Not Been Successful In Significantly Reducing The Severity Of Chronic Pain; Thus, Neurofeedback Training Is a New Approach To The Treatment Of Chronic Musculoskeletal Pain With Better Efficacy Than Other Interventions. The Purpose Of This Review Article Is To Investigating Effectiveness Of Neurofeedback Exercises In Chronic Musculoskeletal Pain Reduction. Material & Methods: The Search Articles From Databases Pubmed, Science Direct, Elsevier, and Springer To Language Both English and Persian Began And Articles From 2000 Up To 2019 Were Extracted. To Extract The Articles, We Used Neurofeedback Pain Treatment, Chronic Pain, And Musculoskeletal Chronic Pain Key Word. 850 Articles Were Found And Aafter Reviewing The Abstract, Titles And Considering The Main Subject Of The Present Study And Criteria Inclusion And Exclusion, 10 Article Were Selected For Final Investigating. Results: After Reviewing 10 Article Related selected, The Results of Those Articles Are Described as Detail in Table 2 and Full in Section Discussion. Conclusion: Neurofeedback Training Appears To Reduce Perceived Pain Severity, But Does Not Treat The Cause Of Pain In This Group Of Patients, Rather Modulates The Response To Pain Processing. As a Result Appears, Combination of Neurofeedback Interventions and Rehabilitation Exercises Be More Effective In Improving the Symptoms of This Group of Patients.

Introduction: Surgery is one of the most widely used health care that High levels of morbidity and mortality is attribute to this care, while half of these outcomes are preventable. The purpose of the present study was to determine the effect of surgical safety checklist on the morbidity and mortality of operated patients. Materials and Methods: The present intervention study was descriptive-analytical and prospective in one of the public hospitals in Tehran. 1604 patients among the operated patients were randomly selected in the control and case groups and their data were extracted with WHO standardized surgical safety checklist. Statistical analysis was performed using descriptive tests (mean, percentage) and analytical tests (chi square) by Stata software. Results: According to the results, there was no significant difference between control and case groups after the implementation of surgical safety checklist in morbidity and mortality of operated patients (P˃ 0. 05). Conclusion: The effectiveness of an instrument depends on a set of conditions that using method and the attitude of the staff towards it is very determinative, Therefore, it seems that completing the surgical safety checklist merely as one of the stages of the surgical process in operating room cannot improve the situation and reduce the morbidity and mortality of the operated patients.

Introduction: The effect of exercise on the expression of genes affecting cardiac hypertrophy is unclear. Evidence suggests that some miRNAs play an important role in improving heart function. The aim of this study was to evaluate the response of miR-133a and some markers of cardiac hypertrophy to endurance training. Methods and Materials: To implementation of this experimental research, 10 male Wistar Rats (4-6 weeks old) randomly were divided into 2 groups control and endurance training. Endurance training performed 5 days a week at a speed of 25 m/min and a gradient of zero degrees for 12 weeks. The expression of miR-133a, IGF-1 and IGF-R genes were measured by Real Time PCR. Data were analyzed by independent t-test at the P<0. 05. Results: The results showed that after 12 weeks of aerobic exercise the expression of MiR-133a and IGF-1 gene was significantly higher in the exercise group than in the control group (P=0. 001). Also, after 12 weeks of aerobic training, no significant difference was observed in IGF-R gene expression between the two groups (P <0. 05). Conclusion: According to the findings of the present study, twelve weeks of aerobic exercise may possibly increase cardiac protection activities through cardiac hypertrophy indices.