Introduction: The need for E-Learning due to its advantages Vs traditional education was felt at any time While in the time of COVID-19 and the absence absent students from the universities, the need for this type of education reached its peak. The purpose of this study is to investigate the factors affecting the inappropriate use of virtual education in the days of Covid 19 from the perspective of students of the Faculty of Rehabilitation, Hamadan University of Medical Sciences. Materials & Methods: The present study is descriptive, cross-sectional. The statistical population of the students of the Faculty of Rehabilitation of Hamadan University of Medical Sciences is 350. According to Morgan table, a sample of 206 people were selected randomly based on the inclusion and exit criteria. A researcher-made questionnaire was used to collect data. To determine the content validity of the questionnaire, the opinions of 10 experts in this field were used, which were examined based on the CVR formula. The total value of the questionnaire was 0. 98, which is an acceptable value based on the Laches table. Also, CVI content validity index for relevance, clarity and simplicity were 0. 89, 0. 93, 0. 90, respectively, which is acceptable considering that they have a value higher than 0. 79. Descriptive test (mean ) and inferential test (exploratory statistics analysis ) were used to analyze the data. These data were analyzed with Spss software version 16. Results: In general, the 8 factors (pedagogical, individual, managerial, administrative, technical, budgetary, organizational, and cultural) explained about 74. 819 percent of the total Variance. The pedagogical factor had the highest proportion in explaining the variance (4. 979 percent) and the cultural factor had the smallest proportion (1. 588 percent). Conclusion: The pedagogical obstacle was the most important problem factor of using e-learning from the viewpoint of the students in the rehabilitation faculty of Hamadan University of Medical Sciences can be resolved by Review the content of education and expressing the content and to engage and activate students.