Background and Aim: Development of fluorosis is increasing due to the higher consumption of fluoride. Microabrasion is the most conservative technique for the management of this disorder. The present study assessed the esthetic improvement of fluorotic teeth after microabrasion with office bleaching.Materials and Methods: This clinical trial was carried out on 20 fluorotic teeth. Microabrasion was performed for 10 minutes followed by office bleaching. Digital images were obtained of all stages of the treatment. The esthetic improvement was determined by visual analogue scale along with the color parameters of L*a*b* and (DE) after microabrasion (M), microabrasion plus office bleaching (MO) and one week later the data were subjected to One-way analysis of variance (ANOVA) for repeated measures, LSD and Friedman tests.Results: No significant differences were found between fluorotic areas and non-fluorotic areas of the teeth after different stages of (M) regarding L*a*b* and DE parameters. The mean DE was estimated to be 10.05, 14.51 and 20.28 for M, MO and one week later, respectively. Significant differences were observed between these stages (p<0.001). In addition, the mean visual analogue scores for these stages were 4.15, 5.22 and 6.36, respectively, which were significantly different (p<0.0001).Conclusion: This study showed that the microabrasion technique significantly improved the esthetic appearance of fluorotic teeth at all stages of treatment. The most improvement was observed with (MO) after one week and the least was related to (M), while immediate results of (MO) were moderate.