In order to study the effect of plant densities on main stem and each one of tillers mortality in different growth stages of wheat, a field experiment was conducted at College of Agriculture, Shahid Chamran University during 1997-98cropping season. Experiment was carried out as factorial and based on RCB design with four replications. Factors were cultivars (Falat, Atrak, Vee/Nac and Maroon) and plant densities (200,300, 400, 500 and 600 plants/m2).Results indicated that, a fewmain stems were lost in different cultivars and plant densities, and did not produce spikes. In cultivars with high tillering potential, main stem mortality was higher. Main stem mortality in Falat, Atrak, Vee/Nac and Maroon cultivars were 15.41, 14.91, 7.91 and 5.74% ,respectively. Comparing various growth stages of tillering termination, booting, an thesis, milk development and ripening, main stem mortality was 0.0, 1.51, 3.96, 7.53 and 10.99% , respectively. By increasing the plant density, main stem mortality was also occurred earlier. Respecting to tillers, from 1st to the last tillers, the mortalitywas higher. For example, in 1st to 6th tiller, the mortality were 54.77,70.93,86.77,96.33,98.70and 100% , respectively. Also, mortality of each tiller occurred earlier.