Hormozgan Medical Journal
Year:2014 | Volume:18 | Issue:2|Papers Count:14

Kangaroo mother care (KMC) is effective care method that avoids aggressive routinely methods in neonatal wards. Objective of this study was comparing KMC with conventional care (incubator) of premature Infant in neonatal ward.This study was a randomized controlled clinical trial that has been done in 17 months. 40 premature neonates whose birth weight was less than 1500gr were enrolled in the study and categorized with stratified randomization in two groups of case and control. The Kangaroo group was subjected to kangaroo care at least 6 hours per day and control group received routine conventional incubator care. Two groups were compared for weight gain, hospitalization period, saturation of arterial oxygen, body temperature, and apnea. The data were analyzed with t test, Chi-Square, fisher’s exact test and Mann Whitney test. P<0.05 was considered as statistically significant.Two groups were similar for base line characteristics. Mean weight gain was 19.3±9.7 gr/day in kangaroo group compared to 17.7±9.5 gr/day in control group (P=0.47). Mean duration of hospitalization mean episode of apnea other variables such as saturation of oxygen and body temperature have not significant difference.At present, in Bandar Abbas children hospital, the KMC method, compare to routine method has no advantage or disadvantage.

Introduction: Coping ways with stress in coronary heart disease patients can lead to significant changes in levels of Cardiac Biomarker Troponin I, but researchers had not explored it empirically. So, the main objective of this study was to identify the relationship between coping ways with stress and Cardiac Biomarker Troponin I and also, finding coping ways that predict changes in the concentration of the cardiac Troponin I.Methods: All CHD patients who referred to Tehran Shahid Rajaie Heart Hospital were target population. 44 patients with CHD admitted to different parts of hospital were selected among eligible patients. In this study, Lazarus coping ways questionnaire- and Troponin I (BioMerieux, Marcy L’Etoil, France) kit was used.Results: The results showed no positive and significant correlation between Emotional Focused Coping Ways (Inefficient) and Cardiac Biomarker Troponin I and also negative and significant correlation between Problem Focused Coping Ways (Efficient) and Cardiac Biomarker Troponin I. Coefficient of positive re-evaluation coping way (b=-0.735) according to the T test indicate that among 8 of coping ways only this variable with 99% confidence can predic the changes related to Cardiac Biomarker Troponin I.Conclusion: In total, we concluded that increase of application in Emotional Focused Coping Ways (Inefficient) lead to increase in levels of Cardiac Biomarker Troponin I and increase of application in problem focused Coping Ways (Efficient) lead to decrease in levels of Cardiac Biomarker Troponin I.

Introduction: Seafood processing wastewater, which contain high concentrations of pollutants discharged to receiving waters, will reduced the quality of these water resources. The present study was conducted to assess the quality and treatability of wastewater result from fish market in Bandar Abbas using coagulation – flocculation process.Methods: This research was a cross sectional study. In this study 12 composite sample of wastewater from the fish market in Bandar Abbas were selected.randomly Variables to assess the quality of the effluent were TSS, COD, BOD5, pH, TP, TKN and FOG. In this study, using jar test apparatus appropriate coagulant was chosen. Then coagulant dose and pH were optimized. Data analyses based on measures of central tendency dispersion were performed using the SPSS 15 software.Results: The results of this study revealed that BOD5, COD, TSS, FOG, TKN and TP were 1200 mg/L, 1760 mg/L, 330 mg/L, 280 mg/L, 104 mg/L and 45.8 mg/L, respectively. These indices were 46, 28, 8, 18, 24 and 2 times respectively greater than the maximum allowable concentration levels for industrial wastewater discharge to receiving waters. Also based on the results, poly aluminum chloride at the optimum dose of 150-17mg/L, the efficiency on COD removal was 75%-90%, the optimum dose of ferric chloride 200-250mg/L, efficiency was 70%-90%, ferrous sulfate with 250-300mg/L, efficiency was 80%-90%, alum with optimal dose 250-300mg/L, efficiency was 60%-70%. Optimum pH values for poly aluminum chloride, ferric chloride, ferrous sulfate and alum were 6-7, 5-6, 5-7 and 5-6, respectively.Conclusion: In order to prevent pollution of coastal waters of Persian Gulf with wastewater originated from fish market of Bandar Abbas, it essential to treat this wastewater. Based on the findings of this study, using coagulation – flocculation process can significantly reduce the COD of wastewater. But it seems that in choosing the appropriate type and dose of coagulants and optimum pH, environmental considerations is important.

Introduction: L-asparaginase is an anti-neoblastic agent used in the chemotherapy of lymphoblastic leukemia. This enzyme is widely distributed among microorganisms, plants and animals, but microorganisms have proved to be a better alternative for L-asparaginase, thus facilitating its large-scale production. Actinomycetes are filamentous, Gram-positive bacteria widely distributed in the marine environment. Secondary metabolites of actinomycetes are important products, especially in food and pharmaceutical industries. The aim of this study was isolation and molecular identification of L-asparaginase producing actinomycetes isolated from Persian Gulf.Methods: In this study, 60 samples were collected from Persian Gulf in Hormozgan, Iran. Starch Casien Agar medium were used for isolation and purification of actinomycetes. All colonieses were screened for L-asparaginase activity with modified M9 medium. L-asparaginase activity was measured by colorimertic method. Based on the enzyme activity, the strain with high L-asparaginase activity were selected and identified by nucleotide sequencing of 16S rRNA gene.Results: Thirty-two colonies of actinomycetes were obtained from sediment and seawater samples, among which 23 isolates were L-asparaginase producers. The strain PG08 with 37´10-2 IU activity showed the highest activity. Based on the analysis 16S rRNA gen sequences of this strain was showed maximum similarity to Streptomyces spp.OS1-33. Conclusion: Actinomycetes isolated from Persian Gulf may be potential source of enzyme L-asparaginase, Streptomyces spp.PG08 with high productivity L-asparaginase can used for chemotherapy of acute lymphoblastic leukemia.

Introduction: Radiation therapy is a stage of therapeutic in the management of tumors that causes normal cells damage. So, Radioprotective drugs injected before radiotherapy to reduce cell damages and death against ionizing radiation. Curcumin is an antioxidant compound. The aim of this study is to investigate the possible protective effect of curcumin against Gamma-Radiation in male rats.Methods: 70 adult male wistar rats randomly divided into 10 groups including: control, sham, Experimental 1 (treatment with maximum of curcumin in amount of 100 mg/ml), Experimental 2 (treatment with medium of curcumin in amount of 50 mg/ml), Experimental 3 (treatment with minimum of curcumin in amount of 25 mg/ml), Experimental 4 (treatment with curcumin in amount of maximum+radiation), Experimental 5 (treatment with curcumin in amount of medium+radiation), Experimental 6 (treatment with curcumin in amount of minimum+radiation), Experimental 7 (solvent+radiation), Experimental 8 (exposure to irradiation). All animals recived Intraperitoneal injection.following, the testis were fixed and section stained with Haematoxyline & Eosin for 15 days Then with using a microscope equipped with a scaled ocular micrometer and image analysis software were histomorphometry.Results: This study showed that Gamma-radiation with dose of 2 Gy caused severe degeneration changes in testicular tissue include significantl decrease of epithelium thickness and the number of spermtogonia, spermatid and spermatozoaand significantly increased the proportion of lumen diameter to seminiferous tubule diameter (P<0.05) and primary spermatocyte compare with control group. So treatment with curcumin balances adverse effects of Gamma-radiation on testis structure and spermatogenesis and leads toaward normal position.Conclusion: These results suggest curcumin have antioxidant properties that make it able to protect testis structure against Gamma-radiation.

Introduction: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder amongst women of reproductive age and is associated with various metabolic perturbations. Chronic low grade inflammation has been reported to participate in the pathogenesis of metabolic syndrome. In this study we examined the effects of 8 weeks aerobic training on serum C-reactive protein level and cardio metabolic risk factors in women with polycystic ovary syndrome.Methods: This semi experimental study was carried out based on pre-test and post-test on experiment and control groups in Arak, Iran. Twenty women with polycystic ovary syndrome (aged 27.75±5.43 yr) selected and randomly divided to training and control groups (10 people for each group). Aerobic training program was performed 50-60 min/d, 3d/wk, for 2 months. Serum C-reactive protein levels (immunoturbidimetric method), body composition (bioelectrical impedance method) and metabolic parameters (enzymatic and radioimmunoassay method) were assessed before and after the training period. The collected data were analyzed using two-way ANOVA.Results: After an 8 week aerobic training, fasting glucose, insulin resistance index, total cholesterol, triglycerides and abdominal fat were significantly decreased (P<0.05). In contrast, CRP concentrations did not change significantly in response to aerobic training. Conclusion: This study demonstrated that 8 weeks of aerobic training causes an improvement in cardio metabolic risk factors in women with polycystic ovary syndrome without change in concentrations of CRP.

Introduction: Depression during pregnancy disturbs daily activities, acceptance of new roles, pregnant woman’s life responsibilities, and pregnancy consequences. The goal of this study is to investigate the association between depression during pregnancy and type of delivery and some personal characteristics.Methods: This is a descriptive analytical study in which the data were collected through cross sectional methode. Primarily, 10 health care centers were randomly selected by draw. The participants included 378 pregnant women (108 depressed and 270 non-depressed). The instrument for collecting was questionnaire wtich was developed in two phases. The first phase was during pregnancy and included both personal characteristics and Beck II standard depression questionnaire and the second phase was after delivery and included the subjects’ type of delivery. Content validity and Cronbach’s alpha were employed for validity and reliability of the questionnaires respectively. The data were analyzed with SPSS 20 and descriptive statistics and Chi-square, t-test, Mane-Witny and Logistic regression were used.Results: Frequency of depression in the population studied was 26.7%.The results showed that there were significant association between depression during pregnancy and type of delivery (P=0.01), the education of pregnant women (P<0.001) and their spouses’ education (P=0.001),the pregnant women’s occupation (P=0.04) and their spouses’ occupation (P=0.009). There was no significant association between depression during pregnancy and the women’ age of pregnancy.Conclusion: The findings of the study suggested to have some instructions in psychic health for midwives and the personnel who provide hygienic-iatric services for pregnant women. Finally, it is importand and necessary to recognize the mothers who are supposed to be depressed and refer them to the advisors or psychiatrists.

Introduction: Physical activity is the most important factor for health related quality of life. This study aimed to determine physical activity and its association with some anthropometric characteristics of the female staffs of Islamic Azad University of Lahijan.Methods: Female staffs of Islamic Azad University of Lahijan participated in this examination for the evaluation. Physical activity of the participants was assessed with RAPA questionnaire. Then some anthropometric characteristics consisted of Body Mass Index (BMI) and Waist to Hip Ratio (WHR) were assessed.Results: The results represented low points of physical activity levels in this group that may be the cause of progression in chronic disease related to inactivity. On the other hand about 46.6 percent of the participants were overweight or obese. WHR in this group were high (about 80% of participants' WHR were up to 0.85). There was not any significant relationship between the levels of physical activity or anthropometric indices with graduation levels (P£0.05). Negative significant relationship was observed between BMI or WHR with physical activity (P£0.05). There was positive and significant relationship between BMI and WHR of the participants (P£0.05).Conclusion: These findings showed the importance of education, information and proper physical activity in escalating anthropometric characteristics of the females.

Introduction: Internet use has become one of the most popular recreational and academic activities for college students because of its convenience and its availability. Increasing use of internet and its psychological consequences needs more attention to mental health for internet operators. The purpose of the present research was evaluation and comparison of psychic health of addicted and non-addicted students to internet in University of Isfahan.Methods: This cross-sectional study was conducted on 150 randomly selected students during 2009-2010 academic year. Yang standard internet addiction questionnaire and SCL_90_R applied for data gathering and data were analyzed by using Pearson correlation coefficient and t-test with SPSS Software.Results: All subscales of SCL- 90 were significantly associated with internet addiction. The university students with internet addiction have higher score in GSI and seven subscale of SCL-90_R contain, OCD, DEP, SOM, ANX, IS, PAR and PHOB compare to non-addicted group (P<0.05). The result of regression analysis showed that OCD was the best predictor of internet addiction.Conclusion: With the increasing use of internet among college students, the consequences of the internet addiction must be taken into account seriously. Educating students regarding the correct usage of the internet would give a tremendous boost in controlling internet addiction among university students.

Introduction: One of the serious complications of intra uterine device (IUD) is uterine perforation and translocation of it to abdominal organs. Translocation is usually accompanied with abdominal or pelvic pain and absence of string in vaginal examination. Therefore, it was decided to report an asymptomatic case of translocation of IUD to small bowel serosa with presence of string in vaginal exam.Patients: A 30 years old woman was candid for elective laparoscopic tubectomy 4 months after IUD insertion. One month after IUD insertion transabdominal ultrasonography showed her IUD in proper position in uterine cavity. During the laparoscopy, tubal ligation omentum and small bowel adhesion to uterus were present .After adhesionlysis the IUD was embedded in serosa of small bowel and the string was present in uterine cavity. So, IUD removal was performed by laparoscopic grasp and there was no post-operative complication.Conclusion: IUD translocation might be asymptomatic and the presence of string in physical exam could not roule out the translocation.

Owing to this fact that most of the mortalities in cancers are as a result of metastasis, study on the involved pathways in metastasis including Epithelial to mesenchymal transition (EMT) would be so critical and important. Up to date, several extensive studies have been carried out to determine the correlation between EMT and cancer and their results have shown that the EMT plays pivotal role in initiation of metastasis, invasion and recurrence of cancer besides drug resistance. In this pathway which is occurred naturally during fetal development and wound healing, cellular phenotype undergone various changes as well as increased in capability of migration and invasion and the involved epithelial cells transform to semi-fibroblast mesenchymal cells. There are some reports that have shown that mesenchymal cells share the same gene expression and phenotype profile with cancer stem cells (CSCs). This probability has enhanced the correlation between cancer and EMT. CSCs are tumor cells that have the ability to self-renew and tumor genesis through differentiation. It was demonstrated that this pathway has led to metastasis through CSCs induction. In this review article, it was attempted to discuss about the current knowledge about the effect of EMT on cancer development such as formation of CSCs, its regulatory factors and also EMT inhibition and cancer treatment.