Hormozgan Medical Journal
Year:2014 | Volume:18 | Issue:1|Papers Count:17

Introduction: Experiments were done to investigate the cardiovascular response to glutamate (Glu) injection in the bed nucleus of stria terminalis (BST) in urethane anesthetized ovariectomized (OVX) or OVX estrogen treated (OVX+E) female Wistar rats. In this study also the effect of glutaminergic system of the rostral ventrolateral medulla (RVLM) on Glu stimulation of cardiovascular response of the BST were investigated.Methods: Experiments were performed on 27 anaesthetized rats divided into two groups of ovarictomized (OVX) and ovarictomized-estrogen treated (OVX+E). Drugs (50 nl), glutamate; (Glu 0.25M/20 nl) was microinjected into the BST and kynurenic acid a nonselective antagonist glutamate receptors (KYN, 5mM/ 50 nl), was microinjected into the RVLM by micropipette and the BST was restimulated at 10, 20, 60 minutes after the injection of KYN into the RVLM. Blood pressure and heart rate were recorded before and throughout each experiment. The means of maximum changes of mean arterial pressure and heart rate were compared between groups of OVX and OVX+E and saline using ANOVA and with preinjection values using paired t-test.Results: Unilateral microinjection of Glu into the BST (control) decreased mean arterial pressure and heart rate, in the OVX+E and OVX. Ipsilateral microinjection of KYN into the RVLM attenuated Glu induced depressor and bradycardic responses to stimulation of the BST 10 minutes after microinjection of KYN in both groups.Conclusion: These data suggest that RVLM cardiovascular sympathetic premotor neurons contain glutamate receptors that mediate in part the depressor and bradycardic responses to stimulation of the BST in the OVX and OVX+E animals.

Introduction: Morphine is an alkaloid from the poppy plant (papaver somniferum) is extracted and used by millions of people around the world and also types of stresses threated such as immobility stress the health of many people. The aim of this study was to investigate the interference of morphine and immobility stress on plasma levels of hormones of ACTH and corticosterone in mature male rats.Methods: In this empirical study, 70 mature male Wistar rats were enrolled as the control, sham and experiment groups, randomly. 3 experimental groups of different types received doses of 10, 20 and 30 mg/kgBW morphine, and 2 experimental group, one received for 2 hours immobility stress and other for 2 hours immobility stress and other plus morphine with doses of 30 mg/kgBW and the sham group received 1cc of saline intraperitoneally for 5 days. 24 hours after the last injection, mice were bled from the heart and hormones of ACTH and corticosterone levels were measured. The data were evaluated using ANOVA and Tuky test.Results: The results showed that the maximum dose of morphine and immobility stress increases plasma levels of ACTH and corticosterone hormones (P<0.001) and simultaneous administration of morphine and immobilization stress enhances the effect of each alone.Conclusion: Morphine and immobility stress intensify their effect on hormones of ACTH and corticosterone. Therefore, further investigation can discover on the role of stress and morphine on disease incidence and disease prevention, in particular psychosomatic in human specimens.

Introduction: Multiple Sclerosis is one of the most common and disabling neurological disease. Some recent studies showed that the possible role of uric acid in the course of the disease. The purpose of this study was to evaluate the level of Cerebro Spinal Fluid and Serum uric acid in patients with multiple sclerosis and compared with control group).Methods: In this study, Cerebro Spinal Fluid (CSF) and serum uric acid were determined in 30 patients with MS and compared with 20 patients with non inflammatory neurological disease (NIND), which were matched with age and sex. Data were analyzed with software SPSS17 and statistical descriptive methods (mean- percentage, SD) and T-test.Results: The mean CSF uric acid in patients was 19 mg/dl (SD=0.12) and in the control group was 0.24 mg/dl (SD=0.19). The mean serum uric acid in patients was 3.95 mg/dl (SD=1.24) and in the control group was 4.04 mg/dl (SD=1.36). There was no significant relationship between Cerebro Spinal Fluid (CSF) uric acid in both groups (Pvalue=0.30), and also there was no relationship between serum uric acid with both groups (Pvalue=0.83).Conclusion: There was no difference in Cerebro Spinal Fluid (CSF) and serum uric acid in patients with multiple sclerosis and control group.

Introduction: Perform heavy exercise training, causing a variety of changes including a reduction in performance. Few human studies have been examined of supplemental w-3 and exercise, then the aim of this study the interactive effect of exercise and w-3 on resting levels of TNF-a and IL-10 in elite Karate and compared with untrained.Methods: In this quasi-experimental 42 healthy young male elite karate and non-athletes, were randomly divided into study groups. Athletes: 1-w-3 and exercise, 2-placebo and exercise, 3-exercise and non-athletes: 1-w-3, 2- placebo, 3-control. Athletes groups performed Pre-season practice in 65% to 80% VO2 max. Consumption w-3 was 1800mg/day for 4 weeks. Blood sampling done 48 hours before, 12 hours fasting after protocol. TNF-a and IL-10 were measured by ELISA and LDL, HDL Enzymatic methods. Mean level was (P£0.05).Results: Exercise training with w-3 for 4 weeks do not have a significant effect on resting levels of IL-10, TNF-a, HDL, LDL (P>0.05). Then w-3 do not have a significant effect in non-athletes (P>0.05).Conclusion: The results showed that Although the consumption of w-3 do not significant changes in TNF-a and IL-10, but can was slightly reduced in TNF-a and increase in the that IL-10, that is confirming its positive effects on inflammatory factors. However, more research seems necessary in this context.

Introduction: Bandar Abbas sewage system is one of the areas in great quality of cockroaches. In spite of passing a short time from exploitation of this system (since 1383), It is necessary considering the cockroaches abundance and the best way of fighting against this insect.Methods: In this investigation four poisons of delta metrine, sypermetrine, Permetrine and Sevin, were selected to test the rate of efficiency on caclerouches in Bandar Abbas sewag system.Results: The results of cockroaches trapping by random cluster sampling of Bandar Abbas sewage system showed that the most abundance of cockroaches is concentrated on the east towns of the city (Pegah, Tohid, etc). In this investigation 458 cockroaches were trapped and all of them were American kind of cockroaches. Among tested poisons, the most effective in destroying of cockroaches was delta metrine by doses of 3.125ml/m².Conclusion: Hot and humid climate in Bandar Abbas is the best conditions for cockroaches. Specially American cockroach’s Dominant population in the city's sewage system is allocated and Delta metrine, Sypermetrine, Permetrine and Sevin pesticides were effective for their removal.

Introduction: The German cockroach, Blattella germanica (L.), is one of the most serious household insect pests. Current control strategies rely heavily upon application of various formulations of insecticides. The purpose of the present study was to test the short-term effects of formulation of capsule suspension in comparison with formulations of wet table powder and emulsifiable concentrate of lambda-cyhalothrin on German cockroach adults and to choose the most appropriate formulation for practical control measures.Methods: Cockroaches were collected by hand catch and trap, and reared at 27±2 c and 60±10% R.H with a photoperiod of 12:12 (L: D) h. Contact toxicity of three types of lambda-cyhalothrin formulations: emulsifiable concentrate- EC (ICON 5 EC), capsule suspension-CS (DEMAND 10 CS) and wettable powder-WP (ICON 10 WP) were compared against German cockroach adults, Blattella germanica (L.) (Blattaria: Blattellidae). Six concentrations of each formulation were used with ten replicates.Results: The Result showed that the most potent formulation was WP with the LC50 values of 9.87 and 12.24 mg ai. m-2 against males and females, respectively. The formulation of CS attained LC50 values of 11.02 and 13.42 mg ai. m-2 and that the formulation of EC attained the values of 12.30 and 15.01 mg ai. m-2 against males and females, respectively.Conclusion: The results demonstrated that the formulation of WP has high insecticidal activity against German cockroach.

Introduction: In synergic effect of exercise training on reducing cardiovascular disease, soy is a useful source of food in reducing blood pressure and control of heart rate. The purpose of this study was to investigate the synergic effect of short aerobic moderate intensity exercise and soya intake on blood pressure & rest heart rate in obese postmenopausal women.Methods: The present study is a Randomized controlled clinical trial in which, 56 obese postmenopausal women randomly divided into four groups (exercise-soya, exercise, soya, and control group). Exercise groups participated in a moderate intensive exercise program for ten weeks, three times (each one, 60 min.) a week with intensity of about 60%-70% maximum heart rate (MHR). The subjects of soya groups had a 100 gram soya nut intake daily for 10 weeks. Before beginning of the exercise training and ten week later, the parameters blood pressure, rest heartbeat, weight and body mass index were measured.Using statistical methods (t test and ANOVA Tow Vey) the data were analyzed.Results: In soy exercise group, before and after the intervention (exercise), the mean of diastolic blood pressure (DBP), systolic blood pressure (SBP), were 87.1±20.7 mmHg and 81.4±16.8 mmHg (P<0.05), 137.2±12.5 mmHg and 130±11.00 mmHg (P<0.05), respectively and in exercise group, Before and after the intervention (exercise), mean of diastolic blood pressure (DBP), systolic blood pressure (SBP), were 89.8±12mmHg, 84.7±10.9 mmHg (P<0.05) and 130±13.9 mmHg, 127.2±7.2 mmHg (P>0.05), respectively. In the cases of resting heart rate, weight, and body mass index, no significant reduction was observed.Conclusion: Based on these results, the moderate intensity aerobic exercise is an effective method for the control of blood pressure in obese postmenopausal women.

Introduction: Psychiatric problems are more common among diabetic patients than general population and can impact on treatment success. Data on psychiatric problems in diabetic patients in Bandarabbas is limited.the aim of this study was to access the prevalence and severity of anxiety and depression in these patients.Methods: In this descriptive cross-sectional study, 100 patients attending Bandar Abbas diabetes clinic were selected simplyand were accessed by Beck anxiety and depression questionnaires. Data analyzed using SPSS 13, Chi-Square and t-test.Results: Prevalence of anxiety and depression was 67 and 50 percent respectively. Both anxiety and depression was more common among females, those with type 2 diabetes and those had at least one complication of diabetes.Conclusion: due to high prevalence of anxiety and depression in these patients routine assessment is indicated.

Introduction: Earth's atmosphere contains billion cubic meters of fresh water, which is considerable as a reliable water resource, especially insultry areas. What is important in this context, how to extract the water, in an economic manner. In order to extract water from air conditioner, no need to spend any cost, because water produced as a by-product and trouble production. The aim of study was to evaluate the quantity and chemical quality of water obtained from Bandar Abbas air conditioners.Methods: This cross-sectional study was conducted during March to December of 2010. Sixty six samples were taken in cluster random plan. Bandar Abbas divided into four clusters; based on distance to shore and population density. Chemical tests which included: turbidity, alkalinity, total hardness, dissolved solids (TDS) and electrical conductivity (EC) and quantity measurement were performed on them. T-test and ANOVA were used for statistical analysis.Results: Obtained water had slightly acidic pH, near to neutral range. Total dissolved solids, electrical conductivity, total hardness and alkalinity of extracted water were in low rate. Each air conditioner produced 36 liter per day averagely. Split types obtained more water to window air conditioners.Conclusion: With regard to some assumptions, approximately 4680 to 9360 cubic meter per day water is obtainable which is suitable for many municipal and industrial water applications.

Introduction: The purpose of this study was to compare agreeableness trait and spiritual health of the addicts living in a community treatment center circuit (TC) and addicts under methadone treatment in Ahvaz.Methods: In this comparative study, the study population consisted of patients referred to outpatient clinics and welfare of people living in boarding centers. A cluster sampling method was used for sample selection. Out of centers, under Behzisti coverage, one community treatment center and 5 outpatient clinics. For addiction treatment were selected randomly. From these centers 100 patient were selected for the study. MANOVA was used for statistical analysis. NEO personality (scale compatibility) and Ellison and Palvtzyn is spiritual health questionnaires were used for data collection.Results: Results show that there are sigfnificant differences in component compatibility and spiritual health mean scores of drug addicts living in community treatment circuits and addicts under methadone treatment (P<0.0001).Conclusion: It seems that living in community treatment centers will tend to increase in their hope and vitality. Living in these centers make them more positive and increase their motivation for treatment contoinuing.

Introduction: During the embossed war, cutaneous leishmaniasis (CL) was considered as a major health problem in war zones, particularly in the South West region of the country. According to this history, monitoring the disease is necessary for military health services. The aim of this study was to determine CL prevalence and temporal condition and mapping of disease between military personnel using Geographic Information System (GIS).Methods: In a descriptive-analytical survey, all records of CL in military units were received from the Department of Health, Health and Medical Education headquarter. Prevalence or incidence rates were calculated and by ArcGIS 9.3 software, storage, and processing of the map was.Results: Maps of CL incidence generated as decision-making facility. Hypothesis about climatic pattern of disease presented. Based on this hypothesis air temperature 28 to 33 degrees, may considered as threshold temperature, one to three months before outbreak.Conclusion: The military endemic CL zones are different from national endemic zones. This phenomenon should be explained by especial military actions, which is different from most of civil occupation. It is necessary for military health system to monitoring reservoirs and zonotic disease in the action fields parallel to disease in the military populations.