To evaluate the prognosis of BHS after iron treatment, 35 children, including 19 boys, and 16 girls, between 3 to 60 months (median age of onset 6 to 24 months) with these attacks were followed prospectively for a period of 3 months after iron treatment. 31 patients had cyanosis, 3 had pallor, and one had mixed attacks. Frequency and severity of their attacks were recorded, before and after our treatment, by their mothers.
All patients were evaluated initially for hematological indices. Complete responses were noticed in 24 patients, favorable response in 9, poor response in 1, and one with no response at all, which were placed in different categories, according to their iron deficiency levels.Among these patients, 14 had iron deficiency anemia, 20 had Iron deficient erythropoieses, and only one with no anemia. Only 2 of them had received regular iron supplement diets, 3 non-regulars, and 30 of them had received no iron supplements. But no marked differences were seen in their responses to the treatment.
The results indicate that iron therapy has an impressive effect in diminution of BHS attacks in infants.