In order to study the effect of plant densities on tillering patterns and its relationship with grain yield of wheat, a field experiment was conducted in College of Agriculture, Shahid Chaml'an University, during 1997-98 year. Experiment was carried out as factorial and based on RCB design with four replications. Factors were wheat cultivars (Falat, Atrak, Vee/Nac and Maroon) and plant densities (200, 300, 400, 500 and 600 Plants/m2). Results indicated that, the effect of cultivar was significant (at %1 level) on total tiller's production coefficient (FTPC), fertile tillers production coefficient (FTPC), number of mortaled tillers per plant, dry matter of mortaled tillers, grain yield, and number of spikes per unit area. For Falat, Atrak, Vee/Nac and Maroon cultivares, FTPC was 2.80, 2.74, 2.20 and 0.62 ; and FTPC was 0.759, 0.740, 0.673 and 0.334, respectively. The dry matter of mortaled tillers was higher, for cultivars with high tillering potential. Atrak with 5728.7 kg/ha and Vee/Nac with 537.8 spikes, had the highest grain yield and number of spikes per unit area, respectively. The effect of plant density was significant on mentioned traits, expect on number of mortaled tillers per plant (at %1 level). The cultivar*plant density interaction was not significant for FTPC, number of mortaled tillers per plant, dry matter of mortaled tillers and grain yield, but was significant for FTPC (at %5 level) and number of spikes per unit area (at %1 level). By increasing the plant density, FTPC, FTPC, number of mortaled tillers per plant and dry matter of mortaled tillers decreased; but number of spikes per unit area increased. The highest grain yield was obtained for Falat and Atrak cultivars at 500 plants/m2, and for Vee/Nac and Maroon cultivars at 600 plants/m2, respectively.