The relationship between serum vitamin D and recurrent aphthous stomatitis (RAS)

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Dolati Mahbobeh; Alaee Arezoo; Farokhnia Taraneh

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

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Journal: Research in Medicine Year:2021 | Volume:45 | Issue:4 Page(s): 66-71

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Information Journal Paper

Title

The relationship between serum vitamin D and recurrent aphthous stomatitis (RAS)

Author(s)

Dolati Mahbobeh | Alaee Arezoo | Farokhnia Taraneh | Issue Writer Certificate

Keywords

Recurrent aphthous stomatitis

Vitamin D

-25Hydroxyvitamin D

Abstract

Background and Aim: Due to the prevalence of Recurrent aphthous stomatitis (RAS) and its complications and the importance of its etiology as well as contradictory reports of the relationship between serum-25HydroxyVitamin D levels and RAS, the present study aimed to determine the relationship between serum-25HydroxyVitamin D levels and RAS in individuals referred to the Department of Oral and Maxillofacial Medicine at the School of Dentistry of the Islamic Azad University of Tehran in 2018. Materials and Methods: The study was conducted using a case control method. The samples included 30 patients: 15 patients with RAS and 15 controls. The two groups were matched in terms of age, sex, and inclusion criteria. Exclusion criteria included suffering from systemic diseases, blood diseases, Behcet's disease, autoimmune diseases, iron deficiency, folate deficiency, and vitamin B12 deficiency as well as multi vitamin, iron, calcium, and Vitamin D consumption during the past 3 months. Each volunteer received 5 ml of blood and their serum-25HydroxyVitamin D level was determined using HPLC device. The quantitative values, in terms of ng/ml, and their qualitative values, based on normal values, were analyzed statistically running t-test and Fisher's exact test. Results: Serum-25HydroxyVitamin D level in the control group was 33. 59 ±,85. 5 ng / ml and was 12. 65±,87. 33 ng / ml in the case group. In terms of quality, %66. 7 in the control group and %40 in the case group had abnormal serum-25HydroxyVitamin D levels. Conclusion: It seems that-25HydroxyVitamin D does not seem to play a role in RAS. For more accurate results, furthure studies with larger sample sizes are recommended.

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References

Vitamin D Levels in Children With Recurrent Aphthous Stomatitis

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APA: Copy

Dolati, Mahbobeh, Alaee, Arezoo, & Farokhnia, Taraneh. (2021). The relationship between serum vitamin D and recurrent aphthous stomatitis (RAS). PAJOUHESH DAR PEZESHKI, 45(4 ), 66-71. SID. https://sid.ir/paper/1008695/en

Vancouver: Copy

Dolati Mahbobeh, Alaee Arezoo, Farokhnia Taraneh. The relationship between serum vitamin D and recurrent aphthous stomatitis (RAS). PAJOUHESH DAR PEZESHKI[Internet]. 2021;45(4 ):66-71. Available from: https://sid.ir/paper/1008695/en

IEEE: Copy

Mahbobeh Dolati, Arezoo Alaee, and Taraneh Farokhnia, “The relationship between serum vitamin D and recurrent aphthous stomatitis (RAS),” PAJOUHESH DAR PEZESHKI, vol. 45, no. 4 , pp. 66–71, 2021, [Online]. Available: https://sid.ir/paper/1008695/en

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