The biological processes related to MicroRNA in fungi; a comprehensive over view

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SADEGHI FATEMEH; Peymaei Fatemeh; Khedri Soleiman; Roudi Raheleh; ROUDBAR MOHAMMADI SHAHLA; ROUDBARY MARYAM

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Journal: Razi Journal of Medical Sciences Year:2018 | Volume:25 | Issue:169 Page(s): 23-36

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Title

The biological processes related to MicroRNA in fungi; a comprehensive over view

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Keywords

MicroRNAQ1

Interfrence RNAQ1

RNA BiologyQ1

Gene silencing related RNAQ1

Abstract

RNA processing is essential factor for synthesis of functional and structural proteins in eukaryote cells. In eukaryote organisms it will be initiated with transcription of DNA in nucleolus and terminated to mRNA translation in cytoplasm, finally mRNA degraded. Protein synthesis followed as different steps, includes 5' capping, poly adenylating, processing and transferring from nucleolus to cytoplasm that all processing control and regulate MicroRNA are small molecules that could be inhibit the translation or degrade the mRNA. Due to the main biological role of RNA in regulation of protein synthesis, it is obvious that fungal pathogenesis is highly related to RNA. Interfrence RNAs (iRNA) are small double strand RNA in fungi that produced by fungal genome or during translation process and play a key role in RNA silencing. Mycovirus is small double strand RNA that led to phenotypic variation in fungi and has a critical role in fungal pathogenesis. The recent studies demonstrated the role of RNA in fungal infection treatment. In this review because of key role of various type of fungal RNA we will discuss our current understanding of the fungal RNA pathways and their functions as well as how RNA can be used as a tool in fungal research especially for immunotherapy of fungal infection.

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APA: Copy

SADEGHI, FATEMEH, Peymaei, Fatemeh, Khedri, Soleiman, Roudi, Raheleh, ROUDBAR MOHAMMADI, SHAHLA, & ROUDBARY, MARYAM. (2018). The biological processes related to MicroRNA in fungi; a comprehensive over view. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 25(169 ), 23-36. SID. https://sid.ir/paper/10169/en

Vancouver: Copy

SADEGHI FATEMEH, Peymaei Fatemeh, Khedri Soleiman, Roudi Raheleh, ROUDBAR MOHAMMADI SHAHLA, ROUDBARY MARYAM. The biological processes related to MicroRNA in fungi; a comprehensive over view. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2018;25(169 ):23-36. Available from: https://sid.ir/paper/10169/en

IEEE: Copy

FATEMEH SADEGHI, Fatemeh Peymaei, Soleiman Khedri, Raheleh Roudi, SHAHLA ROUDBAR MOHAMMADI, and MARYAM ROUDBARY, “The biological processes related to MicroRNA in fungi; a comprehensive over view,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 25, no. 169 , pp. 23–36, 2018, [Online]. Available: https://sid.ir/paper/10169/en

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