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Information Journal Paper

Title

COVID-19 Screening in Rheumatologic Diseases Cases, Special Look at Chloroquine Derivate Use

Pages

  141-147

Abstract

 Background: Among suggested medications for the treatment of COVID-19, Chloroquine derivates and angiotensin-converting–, enzyme inhibitors (ACEIs)/Angiotensin II Type 1 Receptor Blockers (ARBs) are the two medications with conflicting effects on the development of the disease. Objectives: The present study aimed to evaluate COVID-19 in patients with rheumatic diseases receiving Chloroquine derivate. Methods: Every patient with proven rheumatologic diseases registered in two referral centers in Tehran and Alborz, Iran was enrolled in the present descriptive cross-sectional study between May and June 2020. At first, the symptoms of COVID-19 were assessed, and if a case had suspicious symptoms, reverse transcription-polymerase chain reaction (RT-PCR) COVID-19 tests were done. Demographic and clinical data are documented for every patient. Then, the patients were grouped once according to their COVID-19 infection status and another time according to their hydroxyChloroquine use. Results: 1159 patients enrolled in the study with a mean age of 49. 39 years. Frequency of hypertension was 22. 17 %, diabetics (9. 49%) and 20 (1. 7%) patients were positive for COVID-19 testing. The most common symptoms of the COVID-19 positive cases were cough (5. 2%) and fever (4%). There was no significant difference in receiving ACEIs/ARBs or other medications between COVID-19 positive or negative patients. Among the patients receiving hydroxyChloroquine, 15 patients (1. 7%) had proved COVID-19 versus 5 patients (1. 7%) who were not receiving these medications (P>0. 999). Conclusion: The present study demonstrated that receiving ARBs or ACEIs was not different among patients with or without COVID-19. Moreover, receiving Chloroquine derivate was not related to the development of COVID-19 in patients with rheumatologic disorders.

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    Cite

    APA: Copy

    Shadmanfar, Soraya, Alishiri, Gholam Hosein, BAYAT, NOUSHIN, IZADI, MORTEZA, SALIMZADEH, AHMAD, ROSTAMIAN, ABDOLRAHMAN, Abolghasemi, Shahla, Azimzadeh Ardebili, Mohammad Hossein, Rastgar Moqaddam, Zeynab, Hasani, Marjan, RAHMANIAN, EHSAN, Islami, Ghodrat Allah, SABURI, AMIN, & Iranpanah, Helia. (2021). COVID-19 Screening in Rheumatologic Diseases Cases, Special Look at Chloroquine Derivate Use. HOSPITAL PRACTICES AND RESEARCH, 6(4), 141-147. SID. https://sid.ir/paper/1023335/en

    Vancouver: Copy

    Shadmanfar Soraya, Alishiri Gholam Hosein, BAYAT NOUSHIN, IZADI MORTEZA, SALIMZADEH AHMAD, ROSTAMIAN ABDOLRAHMAN, Abolghasemi Shahla, Azimzadeh Ardebili Mohammad Hossein, Rastgar Moqaddam Zeynab, Hasani Marjan, RAHMANIAN EHSAN, Islami Ghodrat Allah, SABURI AMIN, Iranpanah Helia. COVID-19 Screening in Rheumatologic Diseases Cases, Special Look at Chloroquine Derivate Use. HOSPITAL PRACTICES AND RESEARCH[Internet]. 2021;6(4):141-147. Available from: https://sid.ir/paper/1023335/en

    IEEE: Copy

    Soraya Shadmanfar, Gholam Hosein Alishiri, NOUSHIN BAYAT, MORTEZA IZADI, AHMAD SALIMZADEH, ABDOLRAHMAN ROSTAMIAN, Shahla Abolghasemi, Mohammad Hossein Azimzadeh Ardebili, Zeynab Rastgar Moqaddam, Marjan Hasani, EHSAN RAHMANIAN, Ghodrat Allah Islami, AMIN SABURI, and Helia Iranpanah, “COVID-19 Screening in Rheumatologic Diseases Cases, Special Look at Chloroquine Derivate Use,” HOSPITAL PRACTICES AND RESEARCH, vol. 6, no. 4, pp. 141–147, 2021, [Online]. Available: https://sid.ir/paper/1023335/en

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