THE EFFECTS OF CHLORINE ON CELL CYCLE AND DNA CONTENT OF WBC IN MICE

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SHAHIDI M.; MOTEVALIAN M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Paper Information

Journal: Razi Journal of Medical Sciences Year:2005 | Volume:12 | Issue:48 (SPECIAL ISSUE) Page(s): 107-112

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Title

THE EFFECTS OF CHLORINE ON CELL CYCLE AND DNA CONTENT OF WBC IN MICE

Author(s)

SHAHIDI M. | MOTEVALIAN M. | Issue Writer Certificate

Keywords

CHLORINE POISONING - CELL CYCLE - MICE - DNA CONTENTQ4

Abstract

Background & Aim: Chlorine has been known as a mucus membranes and respiratory tract irritant. This gas canincrease free radicals which cause cell damage. The aim of the present study was to measure DNA content and cell cycle inwhite blood cells after chronic chlorine poisoning.Materials & Methods: A clinical experimental study was carried out on 80 male mice(40 mice as sample and 40 ascontrol). The first group was affected by chlorine during 3 weeks and then their blood samples were obtained. Cell cycleand DNA content were measured by flowcytometry.Results: The collected data showed that G0G1, G2M, S phase and DNA index changed significantly in two groups.G0G1 phase decreased and G2M and S phase increased(P<0.05).Conclusion: In conclusion chlorine can significantly affect cell cycle and DNA content and seems to act as a mitogen.

Cites

THE EFFECTS OF INHALING THE TOXIC MIXTURE OF BLEACH AND DETERGENT MATERIALS ON LEUKOCYTES OF MICE

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APA: Copy

SHAHIDI, M., & MOTEVALIAN, M.. (2005). THE EFFECTS OF CHLORINE ON CELL CYCLE AND DNA CONTENT OF WBC IN MICE. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 12(48 (SPECIAL ISSUE)), 107-112. SID. https://sid.ir/paper/10431/en

Vancouver: Copy

SHAHIDI M., MOTEVALIAN M.. THE EFFECTS OF CHLORINE ON CELL CYCLE AND DNA CONTENT OF WBC IN MICE. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2005;12(48 (SPECIAL ISSUE)):107-112. Available from: https://sid.ir/paper/10431/en

IEEE: Copy

M. SHAHIDI, and M. MOTEVALIAN, “THE EFFECTS OF CHLORINE ON CELL CYCLE AND DNA CONTENT OF WBC IN MICE,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 12, no. 48 (SPECIAL ISSUE), pp. 107–112, 2005, [Online]. Available: https://sid.ir/paper/10431/en

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