ASSESSMENT OF THE PREVALENCE OF ANTI H-PYLORI ANTIBODY IN PATIENTS WITH OSTEOARTHRITIS AND HEALTHY PERSONS REFERRED TO BAQIYATOLLAH HOSPITAL, TEHRAN 2006

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ALI SHIRI GH.H.; AMINI MOHSEN; AHMADZADASL MASOUD; GHORBANI GH.A.; JAFARI AMIR MASOUD; SALIMZADEH A.

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Journal: Razi Journal of Medical Sciences Year:2008 | Volume:15 | Issue:58 Page(s): 137-143

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Title

ASSESSMENT OF THE PREVALENCE OF ANTI H-PYLORI ANTIBODY IN PATIENTS WITH OSTEOARTHRITIS AND HEALTHY PERSONS REFERRED TO BAQIYATOLLAH HOSPITAL, TEHRAN 2006

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Keywords

PREVALENCEQ3

HELICOBACTER PYLORIQ3

OSTEOARTHRITISQ2

Abstract

Background & Aim: OSTEOARTHRITIS (OA) is the most frequent disorder seen in the population and imposes a great financial load on the health systems worldwide. This issue necessitates more evaluations to elucidate factors influencing its incidence, severity or clinical presentations. The aim of the present study is to find out whether HELICOBACTER PYLORI (H.pylori) seropositivity differs significantly in patients suffering from OA in comparison with healthy population.Patients and Method: In an analytic observational cross-sectional study, an enzyme-linked immunosorbent assay (ELISA) was used to detect H.pylori specific immunoglobulin G(IgG), immunoglobulin A(IgA) and antibodies against cytotoxin-associated-protein A(anti-Cag A) in 90 patients with OA referred to Baqiyatollah rheumatology clinic and 95 healthy control individuals. For data analysis independent t-test was used.Results: The average age was 53(±0.64) years for 84 women and 6 men in OA group and 39.67(±1.12) years for 78 women and 17 men in the control group. Mean serum IgA level was 40.3(±3.75) and 27.26(±2.05) for OA and control groups respectively. In our evaluation this disparity was statistically significant (P=0.003). Anti H.pylori IgG serum level was not significantly higher in patients with OA in comparison with healthy individuals (P=0.128). Also, anti-CagA antibody serum level did not show a significant difference between OA and control groups (P>0.05).Conclusion: Serum level of anti H.pylori IgA antibody was significantly higher in patients with OA than healthy individuals (p=0.003). This finding was not true for anti-Cag A and IgG antibodies.

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APA: Copy

ALI SHIRI, GH.H., AMINI, MOHSEN, AHMADZADASL, MASOUD, GHORBANI, GH.A., JAFARI, AMIR MASOUD, & SALIMZADEH, A.. (2008). ASSESSMENT OF THE PREVALENCE OF ANTI H-PYLORI ANTIBODY IN PATIENTS WITH OSTEOARTHRITIS AND HEALTHY PERSONS REFERRED TO BAQIYATOLLAH HOSPITAL, TEHRAN 2006. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 15(58), 137-143. SID. https://sid.ir/paper/10456/en

Vancouver: Copy

ALI SHIRI GH.H., AMINI MOHSEN, AHMADZADASL MASOUD, GHORBANI GH.A., JAFARI AMIR MASOUD, SALIMZADEH A.. ASSESSMENT OF THE PREVALENCE OF ANTI H-PYLORI ANTIBODY IN PATIENTS WITH OSTEOARTHRITIS AND HEALTHY PERSONS REFERRED TO BAQIYATOLLAH HOSPITAL, TEHRAN 2006. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2008;15(58):137-143. Available from: https://sid.ir/paper/10456/en

IEEE: Copy

GH.H. ALI SHIRI, MOHSEN AMINI, MASOUD AHMADZADASL, GH.A. GHORBANI, AMIR MASOUD JAFARI, and A. SALIMZADEH, “ASSESSMENT OF THE PREVALENCE OF ANTI H-PYLORI ANTIBODY IN PATIENTS WITH OSTEOARTHRITIS AND HEALTHY PERSONS REFERRED TO BAQIYATOLLAH HOSPITAL, TEHRAN 2006,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 15, no. 58, pp. 137–143, 2008, [Online]. Available: https://sid.ir/paper/10456/en

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