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Information Journal Paper

Title

CHILDHOOD NEUROBLASTOMA: A 10-YEAR STUDY (1991-2001)

Pages

  25-33

Keywords

Not Registered.

Abstract

 Background: Neuroblastoma is the third childhood malignant tumor and is the most common extracranial solid tumor in children, accounting for 10% of childhood cancers. It has a prevalence of ten per million. Patients and Methods: There is an attempt, in this study, to evaluate the patients (less than 18 years of age) with histopathologically-proven diagnosis of neurobalstoma who were referred to hospitals affiliated to the Shiraz University of Medical Sciences over a period of ten years (1991-2001). Results: During this time, 65 patients were admitted with this diagnosis, out of them 38 (58%) were males and 27 (42%) were females. The male to female ratio was 1.4:1. The mean age was 3.5 years with a range of 15 days to 18 years. The most common symptoms of patients at the time admission were fever (48%), anorexia (35%) and abdominal mass (26%). The common signs on admission were fever (42%), hepatomegaly (20%), respiratory distress (17%), diarrhea (15%), convulsion (6%) and proposes (6%). Forty-five percent of the patients had hemoglobin less than 10 mg/dL. Eleven per cent had a WBC count less than 4500. None of the cases were in Stage I, 10 (19.5%) were in Stage TI, 10 (19.5%) in Stage III, 29 (57%) in Stage IV and 2 (4%) in Stage IVs. The primary sites for the tumor were: abdomen (68%), chest (22%) and the neck (5%). Conclusion: In this study, male to female ratio was 1.4:1. Only 18% patients had an age of less than 1 year, 34% were less than 2 years at the time of diagnosis, which showed a delayed diagnosis. The majority of patients (81%) were diagnosed in advanced stages (III, IV and IVs) much more than in similar studies.

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  • Cite

    APA: Copy

    PASALAR, M., MOJARRAB, M., RASEKHI, A.R., AFRASIABI, A.A.R., & YAZDANPANAH, F.. (2003). CHILDHOOD NEUROBLASTOMA: A 10-YEAR STUDY (1991-2001). JOURNAL OF MEDICAL RESEARCH (JMR), 1(4), 25-33. SID. https://sid.ir/paper/105787/en

    Vancouver: Copy

    PASALAR M., MOJARRAB M., RASEKHI A.R., AFRASIABI A.A.R., YAZDANPANAH F.. CHILDHOOD NEUROBLASTOMA: A 10-YEAR STUDY (1991-2001). JOURNAL OF MEDICAL RESEARCH (JMR)[Internet]. 2003;1(4):25-33. Available from: https://sid.ir/paper/105787/en

    IEEE: Copy

    M. PASALAR, M. MOJARRAB, A.R. RASEKHI, A.A.R. AFRASIABI, and F. YAZDANPANAH, “CHILDHOOD NEUROBLASTOMA: A 10-YEAR STUDY (1991-2001),” JOURNAL OF MEDICAL RESEARCH (JMR), vol. 1, no. 4, pp. 25–33, 2003, [Online]. Available: https://sid.ir/paper/105787/en

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