SENSITIVITY PATTERN OF GROUP A BETA HEMOLYTIC STREPTOCOCCI ISOLATED FROM PATIENTS WITH VARIOUS STREPTOCOCCAL INFECTIONS TO PENICILLIN AND OTHER COMMONLY USED ANTIBIOTICS

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KOHANTEB J.; PANJEH SHAHIN M.R.; SADEGHI E.; TABATABAEI H.R.

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Journal Paper

Paper Information

Journal: JOURNAL OF MEDICAL RESEARCH (JMR) Year:2004 | Volume:2 | Issue:3 Page(s): 15-26

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Title

SENSITIVITY PATTERN OF GROUP A BETA HEMOLYTIC STREPTOCOCCI ISOLATED FROM PATIENTS WITH VARIOUS STREPTOCOCCAL INFECTIONS TO PENICILLIN AND OTHER COMMONLY USED ANTIBIOTICS

Author(s)

KOHANTEB J. | PANJEH SHAHIN M.R. | SADEGHI E. | TABATABAEI H.R. | Issue Writer Certificate

Keywords

GROUP A BETA HEMOLYTIC STREPTOCOCCIQ4

MINIMUM INHIBITORY CONCENTRATIONQ3

ANTIBIOTICSQ3

PHARYNGITISQ3

PENICILLINQ3

Abstract

Background: GROUP A BETA HEMOLYTIC STREPTOCOCCI (GABHS) is a potentially pathogenic bacteria which causes various infections among children and adults. For over 60 years, PENICILLIN has been used as the drug of choice for treatment of infections caused by this bacterium. Yet, there is no published article on the resistance of this bacterium to PENICILLIN. However, some species of this family such as enterococci are highly resistant to this antibiotic. Materials and Methods: In the present investigation, 125 isolates of GABHS isolated from patients with PHARYNGITIS, sinusitis and burn infections were subjected to antibiotic sensitivity by standard methods of disk diffusion and MINIMUM INHIBITORY CONCENTRATION (MIC) tests using PENICILLIN, vancomycin, ciprofloxacin, cephalothin, erythromycin, tetracycline and chloramphenicol. Results: All isolates of GABHS (100%) were sensitive to PENICILLIN (MIC: 0.002-0.032 μgr/ml) and vancomycin (MIC: 0.125-2 μgr/ml). Other sensitivity rates included: cephalothin 97.6% (MIC: 0.01-8 μgr/ml), chloramphenicol 88.8% (MIC: 1-32 μgr/ml), erythromycin 87.2% (MIC: 0.032-64 μgr/ml), tetracycline 75.2% (MIC: 0.125-128 μgr/ml) and ciprofloxacin 92.8% (MIC: 0.125-4 μgr/ml). Conclusion: PENICILLIN is still the drug of choice for treatment of GABHS infections. Patients allergic to PENICILLIN are recommended to use erythromycin or other macrolides.

Cites

BETA HEMOLYTIC GROUP A STREPTOCOCCAL DRUG RESISTANT TO PENICILLIN AMONG ASYMPTOMATIC CARRIERS

References

مقاومت باکتری های استرپتوکوک گروه های A,B,D نسبت به اریترومایسین و تتراسیکلین

Cite

APA: Copy

KOHANTEB, J., PANJEH SHAHIN, M.R., SADEGHI, E., & TABATABAEI, H.R.. (2004). SENSITIVITY PATTERN OF GROUP A BETA HEMOLYTIC STREPTOCOCCI ISOLATED FROM PATIENTS WITH VARIOUS STREPTOCOCCAL INFECTIONS TO PENICILLIN AND OTHER COMMONLY USED ANTIBIOTICS. JOURNAL OF MEDICAL RESEARCH (JMR), 2(3), 15-26. SID. https://sid.ir/paper/105806/en

Vancouver: Copy

KOHANTEB J., PANJEH SHAHIN M.R., SADEGHI E., TABATABAEI H.R.. SENSITIVITY PATTERN OF GROUP A BETA HEMOLYTIC STREPTOCOCCI ISOLATED FROM PATIENTS WITH VARIOUS STREPTOCOCCAL INFECTIONS TO PENICILLIN AND OTHER COMMONLY USED ANTIBIOTICS. JOURNAL OF MEDICAL RESEARCH (JMR)[Internet]. 2004;2(3):15-26. Available from: https://sid.ir/paper/105806/en

IEEE: Copy

J. KOHANTEB, M.R. PANJEH SHAHIN, E. SADEGHI, and H.R. TABATABAEI, “SENSITIVITY PATTERN OF GROUP A BETA HEMOLYTIC STREPTOCOCCI ISOLATED FROM PATIENTS WITH VARIOUS STREPTOCOCCAL INFECTIONS TO PENICILLIN AND OTHER COMMONLY USED ANTIBIOTICS,” JOURNAL OF MEDICAL RESEARCH (JMR), vol. 2, no. 3, pp. 15–26, 2004, [Online]. Available: https://sid.ir/paper/105806/en

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