Phototherapy Effects on Zinc Level of Neonates With Hyperbilirubinemia: A Systematic Review and Meta-analysis

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SAROKHANI DIANA; ADIBI AMIR; Abdan Mohsen; FAKHRI MOLOUD

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Journal Paper

Paper Information

Journal: Journal of Pediatrics Review Year:2023 | Volume:11 | Issue:2 (31) Page(s): 107-116

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Information Journal Paper

Title

Phototherapy Effects on Zinc Level of Neonates With Hyperbilirubinemia: A Systematic Review and Meta-analysis

Author(s)

SAROKHANI DIANA | ADIBI AMIR | Abdan Mohsen | FAKHRI MOLOUD | Issue Writer Certificate

Keywords

Zinc

Hyperbilirubinemia

Neonatal jaundice

Jaundice

Neonatal

Phototherapy

Light therapy

Abstract

Background: Phototherapy is the most common treatment of Neonatal Jaundice/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">Neonatal Jaundice that affects the Zinc level as well as the bilirubin level. Objectives: The purpose of this study is to investigate the effect of Phototherapy on the Zinc level of infants with Jaundice by a systematic review and meta-analysis. Methods: In this systematic review and meta-analysis a comprehensive literature search of the databases, including Cochrane Library, Web of Science, PubMed, Scopus, and Google Scholar web browser was conducted using standard keywords. Data analysis of this metaanalysis was performed using STATA software, version 14 and P<0. 05 was considered a significant level for tests. Results: In the five studies reviewed in this article with a sample size of 398 individuals, Phototherapy increased the level of Zinc [Standardized mean difference (SMD): 0. 88 (95% CI: 0. 38, 1. 38), P<0. 001] and decreased bilirubin level [SMD:-7. 67 (95% CI:-9. 11,-6. 23), P<0. 001] in infants with Jaundice. The effect of Phototherapy was on the Zinc level of these groups: infants with a birth weight of 3000 to 3300 grams (gr) [SMD: 1. 07 (95% CI: 0. 42, 1. 71), P<0. 001] and 3301 to 3600 gr [SMD: 0. 40 (95% CI:-0. 32, 1. 12), P=0. 028], three-day-old infants [SMD: 1. 05 (95% CI: 0. 35, 1. 74), P<0. 001], four-day-old [SMD: 0. 76 (95% CI: 0. 26, 1. 32)], and 5-day-old ones [SMD: 0. 23 (95% CI:-0. 01, 0. 48)]. In addition, Phototherapy affected on Zinc level of those whose gestational age (GA) was 37 [SMD: 1. 12 (95% CI: 0. 06, 2. 17), P<0. 001] and 38 [SMD: 0. 61 (95% CI: 0. 15, 1. 06), P=0. 001] weeks. Conclusions: Phototherapy by reducing the level of bilirubin increases the level of Zinc in infants with Jaundice. So, the standardized mean difference of “, Phototherapy effects on the Zinc level of infants with Jaundice”,decreases with increasing infants’,weight, increasing infants’,age, and increasing gestational age.

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APA: Copy

SAROKHANI, DIANA, ADIBI, AMIR, Abdan, Mohsen, & FAKHRI, MOLOUD. (2023). Phototherapy Effects on Zinc Level of Neonates With Hyperbilirubinemia: A Systematic Review and Meta-analysis. JOURNAL OF PEDIATRICS REVIEW, 11(2 (31)), 107-116. SID. https://sid.ir/paper/1069237/en

Vancouver: Copy

SAROKHANI DIANA, ADIBI AMIR, Abdan Mohsen, FAKHRI MOLOUD. Phototherapy Effects on Zinc Level of Neonates With Hyperbilirubinemia: A Systematic Review and Meta-analysis. JOURNAL OF PEDIATRICS REVIEW[Internet]. 2023;11(2 (31)):107-116. Available from: https://sid.ir/paper/1069237/en

IEEE: Copy

DIANA SAROKHANI, AMIR ADIBI, Mohsen Abdan, and MOLOUD FAKHRI, “Phototherapy Effects on Zinc Level of Neonates With Hyperbilirubinemia: A Systematic Review and Meta-analysis,” JOURNAL OF PEDIATRICS REVIEW, vol. 11, no. 2 (31), pp. 107–116, 2023, [Online]. Available: https://sid.ir/paper/1069237/en

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