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Title

Effects of Hypertension Alone and in Comorbidity with Diabetes on Death within 30 Days among Inpatients with COVID-19 Infection

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Abstract

 Background: Hypertension and Diabetes are common Comorbidities in patients with COVID-19 and could be influencing the Mortality of such patients. The present study aimed to evaluate the effects of Hypertension alone and in comorbidity with Diabetes on the death within 30 days among inpatients with COVID-19 in presence of well-known determinates of COVID-19 death. Study Design: A case-control study. Methods: Four groups of COVID-19 inpatients including controls, Diabetes alone, Hypertension alone, and Hypertension and Diabetes Comorbidities were defined. Each study groups did not have underlying diseases other than Hypertension and Diabetes. Demographic and general characteristics, underlying diseases, and hospital course events were extracted from medical records. The outcome of interest was alive at discharge/ death within 30 days after admission. Multivariable binary logistic analysis was employed to estimate the effect measures. Results: The number of death within 30 days among controls (n = 1359), Diabetes alone (159), Hypertension alone (406) and Hypertension and Diabetes Comorbidities (188) were 12. 68%, 15. 72%, 20. 74% and 26. 74%, respectively. According to three multivariable analyses after adjusting older age, hospital length of stay, and intensive care unit (ICU) admission separately, the odds of death within 30 days in COVID-19 patients with having Hypertension and Diabetes Comorbidities was 1. 58, 2. 13 and 1. 91 times of patients without such Comorbidities, respectively (P < 0. 015). The effect of Hypertension alone was also significant after adjusting hospital length of stay and ICU admission but not for older age. Conclusion: Our results suggest that Comorbidities, such as Hypertension and Diabetes may be associated with COVID-19-related deaths independent of other underlying diseases, older age, and adverse hospital course events.

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    APA: Copy

    AYUBI, ERFAN, TORKAMAN ASADI, FATEMEH, BORZOUEI, SHIVA, Alafchi, Behnaz, Faghih Soleimani, Mobin, Khosronejad, Saman, KHAZAEI, SALMAN, & Talebi, Seyed Saman. (2022). Effects of Hypertension Alone and in Comorbidity with Diabetes on Death within 30 Days among Inpatients with COVID-19 Infection. JOURNAL OF RESEARCH IN HEALTH SCIENCES (JRHS), 22(4), 0-0. SID. https://sid.ir/paper/1080382/en

    Vancouver: Copy

    AYUBI ERFAN, TORKAMAN ASADI FATEMEH, BORZOUEI SHIVA, Alafchi Behnaz, Faghih Soleimani Mobin, Khosronejad Saman, KHAZAEI SALMAN, Talebi Seyed Saman. Effects of Hypertension Alone and in Comorbidity with Diabetes on Death within 30 Days among Inpatients with COVID-19 Infection. JOURNAL OF RESEARCH IN HEALTH SCIENCES (JRHS)[Internet]. 2022;22(4):0-0. Available from: https://sid.ir/paper/1080382/en

    IEEE: Copy

    ERFAN AYUBI, FATEMEH TORKAMAN ASADI, SHIVA BORZOUEI, Behnaz Alafchi, Mobin Faghih Soleimani, Saman Khosronejad, SALMAN KHAZAEI, and Seyed Saman Talebi, “Effects of Hypertension Alone and in Comorbidity with Diabetes on Death within 30 Days among Inpatients with COVID-19 Infection,” JOURNAL OF RESEARCH IN HEALTH SCIENCES (JRHS), vol. 22, no. 4, pp. 0–0, 2022, [Online]. Available: https://sid.ir/paper/1080382/en

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