مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

Recent progress in the intranasal PLGA-based drug delivery for neurodegenerative diseases treatment

Pages

  1107-1119

Abstract

 One of the most challenging problems of the current treatments of Neurodegenerative diseases is related to the permeation and access of most therapeutic agents to the central nervous system (CNS), prevented by the blood-brain barrier (BBB). Recently, Intranasal (IN) delivery has opened new prospects because it directly delivers drugs for neurological diseases into the brain via the olfactory route. Recently, PLGA-based nanocarriers have attracted a lot of interest for IN delivery of drugs. This review gathered clear and concise statements of the recent progress of the various developed PLGAbased nanocarriers for IN Drug delivery in brain diseases including Alzheimer’, s, Parkinson’, s, brain tumors, ischemia, epilepsy, depression, and schizophrenia. Subsequently, future perspectives and challenges of PLGA-based IN administration are discussed briefly.

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    Cite

    APA: Copy

    Aghaei Delche, Nasim, Kheiri, Reyhaneh, Ghorbani Nejad, Behnam, Sheikhi, Mojgan, Razavi, Malihe Sadat, Rahimzadegan, Milad, & Salmasi, Zahra. (2023). Recent progress in the intranasal PLGA-based drug delivery for neurodegenerative diseases treatment. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 26(10), 1107-1119. SID. https://sid.ir/paper/1084695/en

    Vancouver: Copy

    Aghaei Delche Nasim, Kheiri Reyhaneh, Ghorbani Nejad Behnam, Sheikhi Mojgan, Razavi Malihe Sadat, Rahimzadegan Milad, Salmasi Zahra. Recent progress in the intranasal PLGA-based drug delivery for neurodegenerative diseases treatment. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2023;26(10):1107-1119. Available from: https://sid.ir/paper/1084695/en

    IEEE: Copy

    Nasim Aghaei Delche, Reyhaneh Kheiri, Behnam Ghorbani Nejad, Mojgan Sheikhi, Malihe Sadat Razavi, Milad Rahimzadegan, and Zahra Salmasi, “Recent progress in the intranasal PLGA-based drug delivery for neurodegenerative diseases treatment,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 26, no. 10, pp. 1107–1119, 2023, [Online]. Available: https://sid.ir/paper/1084695/en

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