Relation of PLCζ,Gene with Sperm and Oocyte Parameters in Infertility Treatment based on Assisted Reproductive Technologies: Review

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Mehrabi Fatemeh; PARSANEZHAD MOHAMMAD EBRAHIM; SHARIATI MEHRDAD; EDALATMANESH MOHAMMAD AMIN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Shahid Sadoughi University of Medical Sciences Year:2023 | Volume:30 | Issue:12 Page(s): 6147-6162

Download Full-Text

Persian Verion

View:

Download:

Cites:

Information Journal Paper

Title

Relation of PLCζ,Gene with Sperm and Oocyte Parameters in Infertility Treatment based on Assisted Reproductive Technologies: Review

Author(s)

Mehrabi Fatemeh | PARSANEZHAD MOHAMMAD EBRAHIM | SHARIATI MEHRDAD | EDALATMANESH MOHAMMAD AMIN | Issue Writer Certificate

Keywords

Infertility

Intracytoplasmic Sperm injection

In-vitro fertilization

Abstract

Introduction: As the world's population increases, the incidence of Infertility is increasing, and Infertility is now considered to affect 8–, 12% of couples worldwide. Assisted reproductive technology (ART) such as in vitro fertilization (IVF) and Intracytoplasmic Sperm injection (ICSI) is revolutionizing the field of reproductive medicine and strives continuously to provide infertile patients with access to appropriate and efficient treatments. However, some causes leading to total/low fertilization rate in ART have been addressed. Phospholipase C zeta (PLCζ, ) is the main sperm-specific factor responsible for triggering oocyte activation (OA). Therefore, PLCζ,abnormalities, including low and absent expression as well as its mutation has been described as one of the fertility rate inducers resulted from the oocyte activation deficiency and sperm parameters abnormalities and failed IVF and ICSI cycles. In this review article we have aimed to focus on the latest information of the PLCζ,published data in the Web of Science, Scopus, Science Direct and PubMed databases and resulted in the failed IVF and ICSI and recurrent ICSI and IVF failure. In addition the investigations on PLCζ,gene and its coded protein in the animals have been also reported. Conclusion: . Studies have shown that the change in PLCζ,expression and its mutations can cause a decrease in the fertilization rate due to egg activation defects and abnormalities in sperm parameters and failure in ART.

Cites

No record.

References

Cite

APA: Copy

Mehrabi, Fatemeh, PARSANEZHAD, MOHAMMAD EBRAHIM, SHARIATI, MEHRDAD, & EDALATMANESH, MOHAMMAD AMIN. (2023). Relation of PLCζ,Gene with Sperm and Oocyte Parameters in Infertility Treatment based on Assisted Reproductive Technologies: Review. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, 30(12 ), 6147-6162. SID. https://sid.ir/paper/1087147/en

Vancouver: Copy

Mehrabi Fatemeh, PARSANEZHAD MOHAMMAD EBRAHIM, SHARIATI MEHRDAD, EDALATMANESH MOHAMMAD AMIN. Relation of PLCζ,Gene with Sperm and Oocyte Parameters in Infertility Treatment based on Assisted Reproductive Technologies: Review. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2023;30(12 ):6147-6162. Available from: https://sid.ir/paper/1087147/en

IEEE: Copy

Fatemeh Mehrabi, MOHAMMAD EBRAHIM PARSANEZHAD, MEHRDAD SHARIATI, and MOHAMMAD AMIN EDALATMANESH, “Relation of PLCζ,Gene with Sperm and Oocyte Parameters in Infertility Treatment based on Assisted Reproductive Technologies: Review,” JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, vol. 30, no. 12 , pp. 6147–6162, 2023, [Online]. Available: https://sid.ir/paper/1087147/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops