ASSESSMENT OF THE THIRD VENTRICLE DIAMETER OF BRAIN IN COMPUTED TOMOGRAPHIC SCANS OF PATIENTS WITH MAJOR DEPRESSIVE DISORDER

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SAEDI D.; YEKRANG SAFAKAR M.; FARID ARAKI K.GH.

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Journal: Razi Journal of Medical Sciences Year:2005 | Volume:11 | Issue:43 Page(s): 771-780

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Title

ASSESSMENT OF THE THIRD VENTRICLE DIAMETER OF BRAIN IN COMPUTED TOMOGRAPHIC SCANS OF PATIENTS WITH MAJOR DEPRESSIVE DISORDER

Author(s)

SAEDI D. | YEKRANG SAFAKAR M. | FARID ARAKI K.GH. | Issue Writer Certificate

Keywords

DEPRESSIONQ2

COMPUTED TOMOGRAPHYQ3

VENTRICLE TO BRAIN RATIOQ4

THIRD VENTRICLEQ4

Abstract

The objective of the present study was to compare the maximum width of the THIRD VENTRICLE (V3) in brain computed tomographic (CT) scans of patients with Major Depressive Disorder (MOD) and normal healthy controls in psychiatry clinics and wards of Iran University of Medical Sciences and radiology Department of Hazrat Rasoul Hospital. First, during a pilot study, interrater and intrarater reliability of the researcher in obtaining CT values were assessed. Then, patients consequently admitted to the psychiatry clinics were included if they met MOD and inclusion criteria, and if they had filled informed consent. Controls who met inclusion criteria were selected from healthy persons admitted to CT department using planimetric and densiometric methods. CT scans of 30 patients and 30 age and sex matched controls were assessed and linear values and ventricular brain ratio (VBR) were measured. Data was assessed by using independent sample, two-tailed t-test and Pearson's correlation coefficient. The mean width of V3 showed significant difference between all age and sex subgroups of patients and controls (P<0.5). There was a significant difference between patients and controls younger than 40 in linear values of frontal lobe, Huckmann number and VBR (P<0.5 in all cases), but no difference was observed in older groups. Correlation assessment showed that the sooner the illness began and the longer its duration was, the greater the maximum width of V3 (r=-0.37 and 0.37 respectively) and interhemispheric fissure (r=-0.39 and 0.39 respectively) were. Also, number of episodes was positively correlated with VBR and maximum width of V3 (r=0.5 and 0.52 respectively). Based on the findings, it could be hypothesized that there is an enlarged THIRD VENTRICLE of the brain in patients with MDD. Also, MDD can accelerate age-related decrease of the brain tissue of the fronal lobe, but does not increase it.

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APA: Copy

SAEDI, D., YEKRANG SAFAKAR, M., & FARID ARAKI, K.GH.. (2005). ASSESSMENT OF THE THIRD VENTRICLE DIAMETER OF BRAIN IN COMPUTED TOMOGRAPHIC SCANS OF PATIENTS WITH MAJOR DEPRESSIVE DISORDER. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 11(43), 771-780. SID. https://sid.ir/paper/10883/en

Vancouver: Copy

SAEDI D., YEKRANG SAFAKAR M., FARID ARAKI K.GH.. ASSESSMENT OF THE THIRD VENTRICLE DIAMETER OF BRAIN IN COMPUTED TOMOGRAPHIC SCANS OF PATIENTS WITH MAJOR DEPRESSIVE DISORDER. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2005;11(43):771-780. Available from: https://sid.ir/paper/10883/en

IEEE: Copy

D. SAEDI, M. YEKRANG SAFAKAR, and K.GH. FARID ARAKI, “ASSESSMENT OF THE THIRD VENTRICLE DIAMETER OF BRAIN IN COMPUTED TOMOGRAPHIC SCANS OF PATIENTS WITH MAJOR DEPRESSIVE DISORDER,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 11, no. 43, pp. 771–780, 2005, [Online]. Available: https://sid.ir/paper/10883/en

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