The Role of Immunosuppression in the Development of COVID-19 in Systemic Lupus Erythematosus Patients: A Brief Report

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Damirchi Mohammadrafi; AGHAIE MEHRDAD; SEDIGHI SIMA; TAVASSOLI SAMANEH; ROSHANDEL GHOLAMREZA; HASSANI MOHAMMAD JAVAD; ABDOLAHI NAFISEH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF MEDICAL SCIENCES (IJMS) Year:2023 | Volume:48 | Issue:1 Page(s): 91-97

Download Full-Text

View:

Download:

Cites:

Information Journal Paper

Title

The Role of Immunosuppression in the Development of COVID-19 in Systemic Lupus Erythematosus Patients: A Brief Report

Author(s)

Keywords

COVID-19

Systemic lupus erythematosus

Hydroxychloroquine

Immunosuppression

SARS-COV2

Abstract

Recently, due to the coronavirus disease 2019 (COVID-19) pandemic, much concern has been raised about patients with chronic diseases who may become more susceptible to the disease. The present cross-sectional study aimed to characterize the clinical course of COVID-19 in patients with Systemic lupus erythematosus (SLE). In addition, a possible correlation between the Immunosuppression state and the incidence of COVID-19 is investigated. In May 2020, 500 SLE patients registered in the database of Golestan Rheumatology Research Center (Golestan province, Iran) were selected for this cross-sectional study. Using a questionnaire, patients were contacted by telephone to collect data including demographic characteristics, disease status, drug use, and new clinical symptoms. Data were analyzed using SPSS software version 24. 0. Of the 500 selected patients, 355 responded to the phone calls and subsequently enrolled in the study. Among the enrolled patients, 25 were classified as COVID-19 positive, including eight hospitalized patients, of which two required intensive care and subsequently died. COVID-19 incidence was significantly lower in the immunosuppressed patients (2. 2% vs. 10%, P=0. 01). There was no significant correlation between Hydroxychloroquine consumption and the incidence of COVID19 in SLE patients. Fever, fatigue, dyspnea, and dry cough were the most common clinical symptoms. Our results showed that COVID-19 incidence was lower in immunosuppressed than the non-immunosuppressed SLE patients. Further studies are required to substantiate the role of Immunosuppression in the development of COVID-19. A preprint version of this study was published at https: //www. researchsquare. com/article/rs-78704/v1 with doi: https: //doi. org/10. 21203/rs. 3. rs-78704/v1

Cites

No record.

References

No record.

Cite

APA: Copy

Damirchi, Mohammadrafi, AGHAIE, MEHRDAD, SEDIGHI, SIMA, TAVASSOLI, SAMANEH, ROSHANDEL, GHOLAMREZA, HASSANI, MOHAMMAD JAVAD, & ABDOLAHI, NAFISEH. (2023). The Role of Immunosuppression in the Development of COVID-19 in Systemic Lupus Erythematosus Patients: A Brief Report. IRANIAN JOURNAL OF MEDICAL SCIENCES (IJMS), 48(1), 91-97. SID. https://sid.ir/paper/1091620/en

Vancouver: Copy

Damirchi Mohammadrafi, AGHAIE MEHRDAD, SEDIGHI SIMA, TAVASSOLI SAMANEH, ROSHANDEL GHOLAMREZA, HASSANI MOHAMMAD JAVAD, ABDOLAHI NAFISEH. The Role of Immunosuppression in the Development of COVID-19 in Systemic Lupus Erythematosus Patients: A Brief Report. IRANIAN JOURNAL OF MEDICAL SCIENCES (IJMS)[Internet]. 2023;48(1):91-97. Available from: https://sid.ir/paper/1091620/en

IEEE: Copy

Mohammadrafi Damirchi, MEHRDAD AGHAIE, SIMA SEDIGHI, SAMANEH TAVASSOLI, GHOLAMREZA ROSHANDEL, MOHAMMAD JAVAD HASSANI, and NAFISEH ABDOLAHI, “The Role of Immunosuppression in the Development of COVID-19 in Systemic Lupus Erythematosus Patients: A Brief Report,” IRANIAN JOURNAL OF MEDICAL SCIENCES (IJMS), vol. 48, no. 1, pp. 91–97, 2023, [Online]. Available: https://sid.ir/paper/1091620/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops