مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

Transforaminal Epidural Autologous Conditioned Serum Injection in the Treatment of Unilateral Lumbar Radicular Pain: A Randomized, Controlled, Double-Blind Clinical Trial

Pages

  0-0

Abstract

 Background: Low Back Pain could related to disc herniation and managed by surgery. Also, less invasive options, including epidural corticosteroid injection, are available,however, it is associated with side effects. This study aimed to evaluate the effectiveness of Autologous Conditioned Serum (ACS) in treating unilateral lumbar radicular pain. Materials and Methods: In this randomized, controlled, double-blind clinical trial study, a total of 68 patients received the transforaminal epidural injection, 28 patients received ACS, and 30 patients received 40 mg triamcinolone. Under fluoroscopic guidance in anterior-posterior and lateral views, a single injection of ACS or triamcinolone was done via the transforaminal epidural technique. Pain intensity was assessed with a visual analogue scale (VAS) and Oswestry disability index (ODI) at three weeks, three months, and six months. Results: A significant reduction in pain intensity was observed in patients of two groups. There was no significant difference between the two groups during the three months of the study. At the final evaluation at six months, the ACS group showed superiority over the triamcinolone based on the VAS score (P<0. 05) and ODI (P=0. 007). Conclusions: ACS therapy is a new effective option in treating lumbar radicular pain due to herniated disc. Since no specific complication has been reported, it can be used as a substitute for corticosteroids in such cases.

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    APA: Copy

    HASHEMI, MASOUD, Moemenzadeh, Siroos, TAHERI, MEHRDAD, DADKHAH, PAYMAN, HOJJATI, SARAH, & VOJDANI, SALMAN. (2022). Transforaminal Epidural Autologous Conditioned Serum Injection in the Treatment of Unilateral Lumbar Radicular Pain: A Randomized, Controlled, Double-Blind Clinical Trial. GALEN MEDICAL JOURNAL, 11(1), 0-0. SID. https://sid.ir/paper/1095612/en

    Vancouver: Copy

    HASHEMI MASOUD, Moemenzadeh Siroos, TAHERI MEHRDAD, DADKHAH PAYMAN, HOJJATI SARAH, VOJDANI SALMAN. Transforaminal Epidural Autologous Conditioned Serum Injection in the Treatment of Unilateral Lumbar Radicular Pain: A Randomized, Controlled, Double-Blind Clinical Trial. GALEN MEDICAL JOURNAL[Internet]. 2022;11(1):0-0. Available from: https://sid.ir/paper/1095612/en

    IEEE: Copy

    MASOUD HASHEMI, Siroos Moemenzadeh, MEHRDAD TAHERI, PAYMAN DADKHAH, SARAH HOJJATI, and SALMAN VOJDANI, “Transforaminal Epidural Autologous Conditioned Serum Injection in the Treatment of Unilateral Lumbar Radicular Pain: A Randomized, Controlled, Double-Blind Clinical Trial,” GALEN MEDICAL JOURNAL, vol. 11, no. 1, pp. 0–0, 2022, [Online]. Available: https://sid.ir/paper/1095612/en

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