Effect of High-Intensity Interval Training and Portulaca Oleracea Extract on CReactive Protein and Tumor Necrosis Factor-Liver Disease

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Javadi Kia Mehdi; Barjaste Yazdi Ameneh; KHAJEI RAMBOD; Hosein Abadi Mohamad Reza

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Journal Paper

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Journal: Journal of North Khorasan University of Medical Sciences Year:2023 | Volume:15 | Issue:2 Page(s): 13-21

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Information Journal Paper

Title

Effect of High-Intensity Interval Training and Portulaca Oleracea Extract on CReactive Protein and Tumor Necrosis Factor-Liver Disease

Author(s)

Javadi Kia Mehdi | Barjaste Yazdi Ameneh | KHAJEI RAMBOD | Hosein Abadi Mohamad Reza | Issue Writer Certificate

Keywords

C-Reactive Protein

High-Intensity Interval Training

Nonalcoholic Fatty Liver

Portulaca Oleracea extract

Tumor Necrosis Factor-α

Abstract

Introduction: The present study aimed to investigate the effect of High-Intensity Interval Training (HIIT) and Portulaca Oleracea extract on serum levels of C-Reactive Protein (CRP) and Tumor Necrosis Factor-α,(TNF-α, ) in rats with Nonalcoholic Fatty Liver disease (NAFLD). Method: A total of 25 male Wistar rats were randomly divided into five groups: healthy control, fatty liver control, Portulaca Oleracea extract, HIIT, and HIIT+Portulaca Oleracea extract. To induce NAFLD, the rats were fed a high-fat diet for 12 weeks. Portulaca Oleracea supplement at 400 mg/kg was given to the experimental groups. HIIT was performed for eight weeks, five sessions per week with seven repetitions of 1 minute at 90% maximum speed accompanied by active rest intervals, including 2 minutes of running at 20% maximum speed. Results: Serum levels of C-Reactive Protein and Tumor Necrosis Factor-α,in Portulaca Oleracea extract, HIIT, and HIIT+Portulaca Oleraceagroups extract groups were significantly lower than the fatty liver control group (P<0. 05). Conclusion: As evidenced by the results of this study, HIIT alone and combined with Portulaca Oleracea extract can exert positive effects on liver inflammation in patients with NAFLD and prevent disease progression.

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APA: Copy

Javadi Kia, Mehdi, Barjaste Yazdi, Ameneh, KHAJEI, RAMBOD, & Hosein Abadi, Mohamad Reza. (2023). Effect of High-Intensity Interval Training and Portulaca Oleracea Extract on CReactive Protein and Tumor Necrosis Factor-Liver Disease. JOURNAL OF NORTH KHORASAN UNIVERSITY OF MEDICAL SCIENCES, 15(2 ), 13-21. SID. https://sid.ir/paper/1096716/en

Vancouver: Copy

Javadi Kia Mehdi, Barjaste Yazdi Ameneh, KHAJEI RAMBOD, Hosein Abadi Mohamad Reza. Effect of High-Intensity Interval Training and Portulaca Oleracea Extract on CReactive Protein and Tumor Necrosis Factor-Liver Disease. JOURNAL OF NORTH KHORASAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2023;15(2 ):13-21. Available from: https://sid.ir/paper/1096716/en

IEEE: Copy

Mehdi Javadi Kia, Ameneh Barjaste Yazdi, RAMBOD KHAJEI, and Mohamad Reza Hosein Abadi, “Effect of High-Intensity Interval Training and Portulaca Oleracea Extract on CReactive Protein and Tumor Necrosis Factor-Liver Disease,” JOURNAL OF NORTH KHORASAN UNIVERSITY OF MEDICAL SCIENCES, vol. 15, no. 2 , pp. 13–21, 2023, [Online]. Available: https://sid.ir/paper/1096716/en

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