The Effects of Lead and Zinc on Asthma: A Systematic Review and Meta-analysis

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

DARABI BEHZAD; KALVANDI GHOLAMREZA; NAJAFI REZA; TAVAN HAMED

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Pediatrics Year:2023 | Volume:33 | Issue:1 Page(s): 0-0

Download Full-Text

View:

Download:

Cites:

Information Journal Paper

Title

The Effects of Lead and Zinc on Asthma: A Systematic Review and Meta-analysis

Author(s)

DARABI BEHZAD | KALVANDI GHOLAMREZA | NAJAFI REZA | TAVAN HAMED | Issue Writer Certificate

Keywords

AsthmaQ4

LeadQ4

ZincQ4

Meta-analysisQ4

Abstract

Context: In recent decades, the growing number of factories and vehicles has accelerated the release of environmental contaminants such as heavy metals. These inhalable pollutants often cause respiratory diseases and can endanger human health. Some heavy metals (e. g., Zinc), on the other hand, are beneficial micronutrients, playing critical roles in the body. Objectives: This systemic review and Meta-analysis study aimed to examine the role of Lead (Pb) and Zinc (Zn) in Asthma. Methods: MeSH keywords, including Lead, Asthma, and Zinc, along with their Persian equivalents were searched in the PubMed, Google, Web of Sciences, Google Scholar, and SID databases. The articles published between 2000 and 2018 were included. For assessing heterogeneity, the Q and I2 statistics were applied. STATA version 14 was used for data analysis. The review was conducted in accordance with the preferred reporting items for systematic reviews and meta-analyses (PRISMA) statement. Results: The frequency of Asthma was 12% (95% CI: 11-13%, P < 0. 001). The frequencies of high blood Lead levels (BLL) in controls and patients with Asthma were 2% (95% CI: 0-2. 03, P < 0. 001) and 3% (95% CI: 0-3. 04, P < 0. 001), respectively. The ratios of BLL of < 5, 5-10, and > 10 , g/dL were found to be 8% (95% CI: 0-9. 7, P < 0. 001), 10% (95% CI: 0. 8-11, P < 0. 001), and 9% (95% CI: 0. 08-11, P < 0. 001), respectively. The forced expiratoryvolume(FEV)wassignificantly correlated with Zinc level. The resultsfrommeta-regression analysis suggested an increasing trend in Asthma occurrence from 2000 to 2018. Conclusions: While Zinc may have been protective against Asthma, Lead was a risk factor for respiratory diseases and Asthma. Educating children and their parents about Lead poisoning may have prevented or reduced Lead intoxication and Asthma in children.

Cites

No record.

References

No record.

Cite

APA: Copy

DARABI, BEHZAD, KALVANDI, GHOLAMREZA, NAJAFI, REZA, & TAVAN, HAMED. (2023). The Effects of Lead and Zinc on Asthma: A Systematic Review and Meta-analysis. IRANIAN JOURNAL OF PEDIATRICS, 33(1), 00-00. SID. https://sid.ir/paper/1098983/en

Vancouver: Copy

DARABI BEHZAD, KALVANDI GHOLAMREZA, NAJAFI REZA, TAVAN HAMED. The Effects of Lead and Zinc on Asthma: A Systematic Review and Meta-analysis. IRANIAN JOURNAL OF PEDIATRICS[Internet]. 2023;33(1):00-00. Available from: https://sid.ir/paper/1098983/en

IEEE: Copy

BEHZAD DARABI, GHOLAMREZA KALVANDI, REZA NAJAFI, and HAMED TAVAN, “The Effects of Lead and Zinc on Asthma: A Systematic Review and Meta-analysis,” IRANIAN JOURNAL OF PEDIATRICS, vol. 33, no. 1, pp. 00–00, 2023, [Online]. Available: https://sid.ir/paper/1098983/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops