COMPARISON OF VASOMOTOR REACTIVITY IN DIABETIC MELLITUS AND NON - DIABETIC MELLITUS PATIENTS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

HAGHI ASHTIANI B.; SINA F.; HABIBI A.H.; MOGHADASI MAHDI

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Razi Journal of Medical Sciences Year:2009 | Volume:16 | Issue:62 Page(s): 105-111

Download Full-Text

Persian Verion

View:

1,125

Download:

Cites:

Information Journal Paper

Title

COMPARISON OF VASOMOTOR REACTIVITY IN DIABETIC MELLITUS AND NON - DIABETIC MELLITUS PATIENTS

Author(s)

HAGHI ASHTIANI B. | SINA F. | HABIBI A.H. | MOGHADASI MAHDI | Issue Writer Certificate

Keywords

DIABETES MELLITUSQ3

CEREBRAL VASOMOTOR REACTIVITYQ3

TRANSCRANIAL DOPPLERQ3

Abstract

Background and Aim: DIABETES MELLITUS (DM) increases the risk of ischemic cerebrovascular diseases two- to four folds as compared to people without diabetes. Macrovascular disease is the leading cause of death among patients with DIABETES MELLITUS. TRANSCRANIAL DOPPLER (TCD) is a noninvasive procedure used to assess the hemodynamic changes in Middle Cerebral Artery (MCA). Knowing the influence of diabetes on brain hemodynamics, is essential for the proper management of cerebrovascular complications in these patients.The aim of this study was to evaluate and compare CEREBRAL VASOMOTOR REACTIVITY in diabetic and nondiabetic patients.Patients and Methods: In this cross-sectional study, TRANSCRANIAL DOPPLER ultrasound was used to measure Peak Systolic Velocity (PSV), End-Diastolic Velocity (EDV), Mean flow velocityes (MV) and Pulsatility Index (PI) in the Middle Cerebral Arteries (MCA) of 53 Diabetic (confirmed as DM by positive laboratory investigations) and 51 non-diabetic patients. CEREBRAL VASOMOTOR REACTIVITY (VMR) was measured as percentage of changes in peak flow velocity in MCA after inhalation of 5% CO2 for 1-2 minutes. Statistical analysis was done via Independent t-Test and Fischers Exact Test.Results: Non-diabetic patients had higher mean flow velocity as compared to diabetic (53.34±16.7cm/s, 42.47±29cm/s, respectively) which showed significant statistical difference (p=0.021).Also, diabetic group had significantly decreased VMR compared with non diabetics (%5.31±2.6, %6.66±2, respectively) which showed significant statistical difference (p=0.022).Conclusion: According to the results of this study, mean VMR in diabetics was significantly lower than the non-diabetics (%5.31±%2.6 versus %6.66±2 respectively). This means decrease in cerebrovascular reversal capacity and increase risk of cerebrovascular disease in diabetic patients. However, whether diabetes alone is a risk factor for cerebral vascular disease or not, needs more investigations.

Cites

No record.

References

No record.

Cite

APA: Copy

HAGHI ASHTIANI, B., SINA, F., HABIBI, A.H., & MOGHADASI, MAHDI. (2009). COMPARISON OF VASOMOTOR REACTIVITY IN DIABETIC MELLITUS AND NON - DIABETIC MELLITUS PATIENTS. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 16(62), 105-111. SID. https://sid.ir/paper/11023/en

Vancouver: Copy

HAGHI ASHTIANI B., SINA F., HABIBI A.H., MOGHADASI MAHDI. COMPARISON OF VASOMOTOR REACTIVITY IN DIABETIC MELLITUS AND NON - DIABETIC MELLITUS PATIENTS. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2009;16(62):105-111. Available from: https://sid.ir/paper/11023/en

IEEE: Copy

B. HAGHI ASHTIANI, F. SINA, A.H. HABIBI, and MAHDI MOGHADASI, “COMPARISON OF VASOMOTOR REACTIVITY IN DIABETIC MELLITUS AND NON - DIABETIC MELLITUS PATIENTS,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 16, no. 62, pp. 105–111, 2009, [Online]. Available: https://sid.ir/paper/11023/en

Related Journal Papers