THE EFFECT OF WATER IMMERSION STRESS ON LATE PHASE ISOLATED STOMACH FUNDUS STRIP MOTILITY OF RAT

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

PAZOUKI TOROUDI H.R.; TAVAKOULI HOSSEINI M.; TAHER GOURABI Z.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Razi Journal of Medical Sciences Year:2006 | Volume:13 | Issue:50 Page(s): 27-32

Download Full-Text

Persian Verion

View:

919

Download:

Cites:

Information Journal Paper

Title

THE EFFECT OF WATER IMMERSION STRESS ON LATE PHASE ISOLATED STOMACH FUNDUS STRIP MOTILITY OF RAT

Author(s)

PAZOUKI TOROUDI H.R. | TAVAKOULI HOSSEINI M. | TAHER GOURABI Z. | Issue Writer Certificate

Keywords

STOMACHQ2

WATER IMMERSION STRESSQ3

ISOLATED FUNDUSQ3

Abstract

Background & Aim: Gastric ulcer is the result of imbalance between the effect of protective and destructive factors on gastric mucosal layer. There are so many proposed destructive factors including acid, bile, nonsteroidal anti-inflammatory drugs(NSAIDS) and increased gastric motility. In this study we examined the time course effect of WATER IMMERSION STRESS on gastric motility.Material & Methods: Male wistar rats were immersed in 20-25°C water for 2 hours. After water immersion the rats were sacrificed at 30 min, 1 h, 6 h, 12 h and 24 h intervals and the STOMACHes were excised. Transverse strips of the fundus region were prepared and placed in organ bath containing modified Krebs solution perfused with carbogen gas (95% O2, 5% CO2) at 37°C. The contractile activity of the strip was recorded using an isotonic transducer (preload 2g) on NarcoBioSystem physiograph. The amplitude and frequency of the spontaneous contractions were compared to their relevant control groups using student t-test (Pvalue<0.05).Results: No significant change was noticed between the WATER IMMERSION STRESS groups and their relevant controls except in 24 h group. The amplitude of spontaneous contractions increased by 161%. Conclusion: In previous studies it has been shown that shortly after WATER IMMERSION STRESS, gastric mortility increases in live rats. In the ISOLATED FUNDUS strip model, it was noticed that the increase in contractile activity of the STOMACH occurred only 24 hours after WATER IMMERSION STRESS. This may lead us to the conclusion that there are gastric as well as nongastric factors involved in water immersion induced gastric hypermotility. Nongastric factors (e.g. vagus nerve, systemic hormones and …) act rapidly and their effect can be seen shortly after the stress in live animal models. However, in ISOLATED FUNDUS strip model, which is free from nongastric factors, a late increase in gastric motility can be seen. This may be due to the synthesis of cell made products like Immediately Early Genes (IEGs), Heat Shock Proteins (HSPs) and so on. Further work is needed to prove this theory.

Cites

No record.

References

No record.

Cite

APA: Copy

PAZOUKI TOROUDI, H.R., TAVAKOULI HOSSEINI, M., & TAHER GOURABI, Z.. (2006). THE EFFECT OF WATER IMMERSION STRESS ON LATE PHASE ISOLATED STOMACH FUNDUS STRIP MOTILITY OF RAT. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 13(50), 27-32. SID. https://sid.ir/paper/11043/en

Vancouver: Copy

PAZOUKI TOROUDI H.R., TAVAKOULI HOSSEINI M., TAHER GOURABI Z.. THE EFFECT OF WATER IMMERSION STRESS ON LATE PHASE ISOLATED STOMACH FUNDUS STRIP MOTILITY OF RAT. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2006;13(50):27-32. Available from: https://sid.ir/paper/11043/en

IEEE: Copy

H.R. PAZOUKI TOROUDI, M. TAVAKOULI HOSSEINI, and Z. TAHER GOURABI, “THE EFFECT OF WATER IMMERSION STRESS ON LATE PHASE ISOLATED STOMACH FUNDUS STRIP MOTILITY OF RAT,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 13, no. 50, pp. 27–32, 2006, [Online]. Available: https://sid.ir/paper/11043/en

Related Journal Papers