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Information Journal Paper

Title

Inflammation and JAK/STAT Signaling: New Clues for the Treatment of COVID-19

Pages

  98-103

Abstract

 The coronavirus disease 19 (COVID-19) outbreak in Wuhan, Hubei province, is a global health problem affecting about 212 countries around the world, highlighting the importance of the global recruitment of scientists to find a way for managing this burden. So far, many studies have been conducted to find a treatment for COVID-19, some of which indicated promising results. In this situation, gathering the previously published evidence may provide new hypotheses/ solutions in this regard. Based on the role of Inflammation in COVID-19-related deaths, we attempted to find a rational relationship between Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling and COVID-19 and inform JAK/STAT signaling inhibitors as candidates to manage or even prevent severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) infection. Therefore, it is hoped that the present study provides new clues about the relationship between JAK/STAT signaling and the SARS-CoV-2 infection to highlight the role of JAK/STAT inhibitors as a possible treatment for managing inflammatory situations observed in the SARS-CoV-2 infection.

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    Cite

    APA: Copy

    Shirazinia, Reza, AFSHARI, MAHDI, Golabchifar, Ali Akbar, Arab, Hosein Ali, & PANAHI MISHKAR, ABOLFAZL. (2022). Inflammation and JAK/STAT Signaling: New Clues for the Treatment of COVID-19. INTERNATIONAL JOURNAL OF BASIC SCIENCE IN MEDICINE, 7(3), 98-103. SID. https://sid.ir/paper/1112071/en

    Vancouver: Copy

    Shirazinia Reza, AFSHARI MAHDI, Golabchifar Ali Akbar, Arab Hosein Ali, PANAHI MISHKAR ABOLFAZL. Inflammation and JAK/STAT Signaling: New Clues for the Treatment of COVID-19. INTERNATIONAL JOURNAL OF BASIC SCIENCE IN MEDICINE[Internet]. 2022;7(3):98-103. Available from: https://sid.ir/paper/1112071/en

    IEEE: Copy

    Reza Shirazinia, MAHDI AFSHARI, Ali Akbar Golabchifar, Hosein Ali Arab, and ABOLFAZL PANAHI MISHKAR, “Inflammation and JAK/STAT Signaling: New Clues for the Treatment of COVID-19,” INTERNATIONAL JOURNAL OF BASIC SCIENCE IN MEDICINE, vol. 7, no. 3, pp. 98–103, 2022, [Online]. Available: https://sid.ir/paper/1112071/en

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