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Information Journal Paper

Title

Atomoxetine Versus Combination of Methylphenidate Plus Fluoxetine for Management of Anxiety Disorders in ADHD Children: A Randomized Clinical Trial

Pages

  0-0

Abstract

 Background: Attention-defi, cit/hyperactivity disorder (ADHD) is the most common psychiatric disorder in childhood. Concurrent Anxiety Disorders have turned into a challenging issue for psychiatrists. Numerous medications have been applied with controversial responses. Objectives: The current study aimed to compare the effi, cacy of the combination of methylphenidate (MPH) and fl, uoxetine (FLX) versus Atomoxetine (ATX) in the symptoms and function of ADHD children with concurrent Anxiety Disorders. Methods: The current randomized clinical was conducted on 76 outpatient children with concurrent ADHD and Anxiety Disorder within 2020-2021. The patients were divided into two equal groups. The fi, rst group was treated with MPH (5 mg twice daily) plus FLX (10-20 mg daily),nevertheless, the second group received ATX with a dose of 1. 4 mg/kg. The Conner’, s Parents Rating Scale (CPRS), Screen for Child Anxiety Related Emotional Disorders (SCARED), and Children’, s Anxiety Impact Scale-Child (CAIS-C) were applied to assess anxiety at the baseline and 1 month and 4 months after the interventions. Results: The mean age of the studied population was 9. 26 ±,1. 92 years (range: 6-12 years), and 46 subjects (57. 89%) were male. The signifi, cant trends of improvement in both groups, regardless of the interventions in the assessments of all the scales, were noted (P < 0. 001 for all the scales),however, the comparison of the groups revealed no diff, erences in the CPRS (P = 0. 397), SACRED (P = 0. 663), and CAIS-C (P = 0. 683). Conclusions: Based on the fi, ndings of this study, as ATX alone was as eff, ective as MPH plus FLX for controlling Anxiety Disorders among ADHD children, ATX is preferred to apply fewer daily medications.

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    APA: Copy

    Karbasi, Afsaneh, & Aghili, Shahrzad. (2023). Atomoxetine Versus Combination of Methylphenidate Plus Fluoxetine for Management of Anxiety Disorders in ADHD Children: A Randomized Clinical Trial. IRANIAN JOURNAL OF PSYCHIATRY AND BEHAVIORAL SCIENCES (IJPBS), 17(2), 0-0. SID. https://sid.ir/paper/1113141/en

    Vancouver: Copy

    Karbasi Afsaneh, Aghili Shahrzad. Atomoxetine Versus Combination of Methylphenidate Plus Fluoxetine for Management of Anxiety Disorders in ADHD Children: A Randomized Clinical Trial. IRANIAN JOURNAL OF PSYCHIATRY AND BEHAVIORAL SCIENCES (IJPBS)[Internet]. 2023;17(2):0-0. Available from: https://sid.ir/paper/1113141/en

    IEEE: Copy

    Afsaneh Karbasi, and Shahrzad Aghili, “Atomoxetine Versus Combination of Methylphenidate Plus Fluoxetine for Management of Anxiety Disorders in ADHD Children: A Randomized Clinical Trial,” IRANIAN JOURNAL OF PSYCHIATRY AND BEHAVIORAL SCIENCES (IJPBS), vol. 17, no. 2, pp. 0–0, 2023, [Online]. Available: https://sid.ir/paper/1113141/en

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