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Information Journal Paper

Title

Study of safety and efficacy of cream containing oats and chamomile extract in improving the skin lesions of mild and moderate atopic dermatitis

Pages

  71-81

Abstract

 Background and Aim: In order to overcome the local side effects of the conventional treatments for atopic dermatitis, a new attitude regarding alternative treatments would be needed, which herbal medicines are promising approachs in this case. Methods: It was a 4-week, before-after clinical study, conducted on 20 participants (16 women and 4 men) aged 39. 95±, 11. 04 years. The severity scoring of atopic dermatitis was determined based on total & local SCORAD. skin biophisical parameters including TEWL, skin hydration, pH, temperature, sebum and skin erythema were also measured after 2 and 4 weeks application of the study product. Participants’,satisfaction as well as tolerability of the product were assessed by monitoring the adverse effects. Results: A significant improvement was detected in LOCAL and TOTAL SCORAD at weeks 2 and 4 (P<0. 01). The intensity of burning and pruritus also showed a significant decrease at weeks 2 and 4 (P<0. 01). A significant increase in the skin hydration was shown at weeks 2 and 4 after treatment (P<0. 01). 84. 1% and 78. 9% of participants described their skin lesions as "improved" or "much improved", 2 and 4 weeks after treatment respectively. Conclusion: The test cream containing oats and chamomile extract is considered a safe and effective product for improving mild to moderate lesions of atopic dermatitis.

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    Cite

    APA: Copy

    Ahmadian Yazdi, Hasti, FIROOZ, ALIREZA, Rezaeian Vaghar, Mohsen, Kashani, Elahe, & SAMADI, ANISEH. (2023). Study of safety and efficacy of cream containing oats and chamomile extract in improving the skin lesions of mild and moderate atopic dermatitis. DERMATOLOGY AND COSMETIC, 14(2 ), 71-81. SID. https://sid.ir/paper/1113861/en

    Vancouver: Copy

    Ahmadian Yazdi Hasti, FIROOZ ALIREZA, Rezaeian Vaghar Mohsen, Kashani Elahe, SAMADI ANISEH. Study of safety and efficacy of cream containing oats and chamomile extract in improving the skin lesions of mild and moderate atopic dermatitis. DERMATOLOGY AND COSMETIC[Internet]. 2023;14(2 ):71-81. Available from: https://sid.ir/paper/1113861/en

    IEEE: Copy

    Hasti Ahmadian Yazdi, ALIREZA FIROOZ, Mohsen Rezaeian Vaghar, Elahe Kashani, and ANISEH SAMADI, “Study of safety and efficacy of cream containing oats and chamomile extract in improving the skin lesions of mild and moderate atopic dermatitis,” DERMATOLOGY AND COSMETIC, vol. 14, no. 2 , pp. 71–81, 2023, [Online]. Available: https://sid.ir/paper/1113861/en

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