Necrosis of the Tongue as a Late Complication of Radiotherapy

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Aguiar Cristina; Pina Paulo; Medeiros Nuno; Teixeira Monica; Ribeiro Leandro; Oliveira Pedro

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Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF OTORHINOLARYNGOLOGY Year:2023 | Volume:35 | Issue:5 (130) Page(s): 285-288

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Information Journal Paper

Title

Necrosis of the Tongue as a Late Complication of Radiotherapy

Author(s)

Keywords

Late complications

Radiotherapy

Small-vessel disease

Tongue necrosis

Abstract

Introduction: Irradiation to treat head and neck cancer, causing chronic tissue damage, is associated with the development of vascular disease. Interest has risen over the effects of Radiotherapy on major vessels, due to its high morbidity and mortality rate. However, Small-vessel disease has been poorly studied and described. Case Report: We present a case of a patient with bilateral necrosis of the anterior third of the tongue, occurring 3 years after chemoRadiotherapy treatment for squamous cell carcinoma of the floor of the mouth. Contrast-enhanced CT scan showed multiple areas of stenosis concerning both external carotid arteries and their branches, and total opacification of lingual arteries. Conservative management was performed, with auto-amputation on the fifth day, which allowed healing by secondary intention. Conclusions: Necrosis of the tongue appears as a rare late complication of Radiotherapy, possibly due to its acceleration effect on the atherosclerosis process. Following Small-vessel disease, one can assume a higher potential risk of major-vessel disease, highlighting the importance of a routine assessment and prophylaxis of thrombotic events.

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References

Induction Chemotherapy Followed by Radiation Therapy Versus Surgery Followed by Concurrent Chemo-Radiation Therapy in Locally Advanced Squamous Cell Carcinoma of the Oral Cavity

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APA: Copy

Aguiar, Cristina, Pina, Paulo, Medeiros, Nuno, Teixeira, Monica, Ribeiro, Leandro, & Oliveira, Pedro. (2023). Necrosis of the Tongue as a Late Complication of Radiotherapy. IRANIAN JOURNAL OF OTORHINOLARYNGOLOGY, 35(5 (130)), 285-288. SID. https://sid.ir/paper/1118689/en

Vancouver: Copy

Aguiar Cristina, Pina Paulo, Medeiros Nuno, Teixeira Monica, Ribeiro Leandro, Oliveira Pedro. Necrosis of the Tongue as a Late Complication of Radiotherapy. IRANIAN JOURNAL OF OTORHINOLARYNGOLOGY[Internet]. 2023;35(5 (130)):285-288. Available from: https://sid.ir/paper/1118689/en

IEEE: Copy

Cristina Aguiar, Paulo Pina, Nuno Medeiros, Monica Teixeira, Leandro Ribeiro, and Pedro Oliveira, “Necrosis of the Tongue as a Late Complication of Radiotherapy,” IRANIAN JOURNAL OF OTORHINOLARYNGOLOGY, vol. 35, no. 5 (130), pp. 285–288, 2023, [Online]. Available: https://sid.ir/paper/1118689/en

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