Effect of Vitamin D on Lung Function, Serum Immunoglobulin E and Total Antioxidant Capacity in Asthma Patients: A Clinical Trial

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MORTAZAVIMOGHADDAM SAYYED GHOLAMREZA; ZARBAN ASGHAR; MIRSHAHI ALI

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Journal Paper

Paper Information

Journal: Journal of Gorgan University of Medical Sciences Year:2022 | Volume:24 | Issue:3 (83) Page(s): 1-7

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Information Journal Paper

Title

Effect of Vitamin D on Lung Function, Serum Immunoglobulin E and Total Antioxidant Capacity in Asthma Patients: A Clinical Trial

Author(s)

MORTAZAVIMOGHADDAM SAYYED GHOLAMREZA | ZARBAN ASGHAR | MIRSHAHI ALI | Issue Writer Certificate

Keywords

Asthma

Vitamin D

Immunoglobulin E

Abstract

Background and Objective: Asthma is a chronic airway disorder with a rising prevalence. Dietary factors, antioxidant indicators and Vitamin D deficiency are associated with the disease. Due to the presence of receptors for this vitamin in the lung, this study aimed to investigate the effects of Vitamin D administration on lung function, serum Immunoglobulin E (IgE) level and total serum antioxidant activity in patients with moderate to severe Asthma. Methods: In this clinical trial, 60 patients with Asthma were randomly divided into two groups: a control group (placebo recipient) and an intervention group (recipient of 2, 000 Vitamin D capsules for 12 weeks). At the beginning and at the end of the study, 5 cc blood samples were taken from each patient, and spirometry test was performed. Total antioxidant capacity (TAC), IgE and Vitamin D parameters were measured. Results: The mean score of forced expiratory volume (FEV1) and FEV1/FVC in both groups as well as the mean FVC in the control group did not change significantly after the intervention. The mean FVC score, Vitamin D level and TAC in the intervention group increased significantly after the intervention, while the IgE levels reduced significantly. Conclusion: Taking Vitamin D tablets could increase the antioxidant parameters in Asthmatic patients.

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APA: Copy

MORTAZAVIMOGHADDAM, SAYYED GHOLAMREZA, ZARBAN, ASGHAR, & MIRSHAHI, ALI. (2022). Effect of Vitamin D on Lung Function, Serum Immunoglobulin E and Total Antioxidant Capacity in Asthma Patients: A Clinical Trial. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, 24(3 (83) ), 1-7. SID. https://sid.ir/paper/1126769/en

Vancouver: Copy

MORTAZAVIMOGHADDAM SAYYED GHOLAMREZA, ZARBAN ASGHAR, MIRSHAHI ALI. Effect of Vitamin D on Lung Function, Serum Immunoglobulin E and Total Antioxidant Capacity in Asthma Patients: A Clinical Trial. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2022;24(3 (83) ):1-7. Available from: https://sid.ir/paper/1126769/en

IEEE: Copy

SAYYED GHOLAMREZA MORTAZAVIMOGHADDAM, ASGHAR ZARBAN, and ALI MIRSHAHI, “Effect of Vitamin D on Lung Function, Serum Immunoglobulin E and Total Antioxidant Capacity in Asthma Patients: A Clinical Trial,” JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, vol. 24, no. 3 (83) , pp. 1–7, 2022, [Online]. Available: https://sid.ir/paper/1126769/en

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