Effects of Endurance Training and Propolis Against Oxidative and Myocardial Stress in Diabetic Ovariectomized Rats

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Hasanzadeh Dolatabadi Fatemeh; JALALI DEHKORDI KHOSRO; TAGHIAN FARZANEH; HOSEINI SEYED ALI

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Gorgan University of Medical Sciences Year:2023 | Volume:24 | Issue:4 (84) Page(s): 51-58

Download Full-Text

Persian Verion

View:

Download:

Cites:

Information Journal Paper

Title

Effects of Endurance Training and Propolis Against Oxidative and Myocardial Stress in Diabetic Ovariectomized Rats

Author(s)

Hasanzadeh Dolatabadi Fatemeh | JALALI DEHKORDI KHOSRO | TAGHIAN FARZANEH | HOSEINI SEYED ALI | Issue Writer Certificate

Keywords

Endurance Training

Propolis

Oxidative Stress

HSP 72

Heart

Ovariectomy

Diabetes Mellitus

Abstract

Background and Objective: Considering the role of diet and the use of natural antioxidants in addition to exercise, the attention of researchers has been drawn to take further advantage of the effects of exercise to improve cellular metabolism. Despite the favorable role of exercise and antioxidants on Heart health, the simultaneous effect of exercise and consumption of Propolis (prepared by bees) is not yet known. This study aimed to investigate the effects of Endurance Training and Propolis against oxidative and myocardial stress in diabetic ovariectomized rats. Methods: This experimental study was conducted on 36 female Sprague Dawley rats aged 12-16 weeks and weighing 220-250 grams. Six rats were included in the healthy control group. Diabetes was induced in 30 overiectomized rats by intraperitoneal injection of streptozotocin (40 mg/kg). Then, the diabetic animals were divided into five groups of six including diabetic ovariectomized control, sham, Propolis, Endurance Training, and Endurance Training + Propolis. Rats in the training groups trained for eight weeks, five sessions per week, with 55-75% VO2 max. Moreover, Propolis was administered 100 mg/kg/day by peritoneal injection. The level of Pro-oxidant-antioxidant balance (PAB) and expression of HSP72 and NF-κ, B genes were measured. Results: HSP72 expression was significantly higher in the Propolis, Endurance Training, and Endurance Training + Propolis groups. The levels of NF-kB and malonaldehyde were significantly decreased in the ovariectomized diabetic rats (P<0. 05). Expression of HSP72 in the Endurance Training and Endurance Training + Propolis groups were significantly higher than in the Propolis group. Moreover, NF-kB in the Endurance Training and Endurance Training + Propolis groups were significantly lower than in the Propolis group (P<0. 05). The value of PAB in the Propolis and Endurance Training + Propolis groups were significantly lower than in the ovariectomized diabetic rats (P<0. 05). Conclusion: Exercise and consumption of Propolis seem to synergistically improve the protective HSP72 pathway and reduce Oxidative Stress in Heart tissue following estrogen dysfunction and diabetes. However, the interaction of the two depends on Endurance Training.

Cites

No record.

References

No record.

Cite

APA: Copy

Hasanzadeh Dolatabadi, Fatemeh, JALALI DEHKORDI, KHOSRO, TAGHIAN, FARZANEH, & HOSEINI, SEYED ALI. (2023). Effects of Endurance Training and Propolis Against Oxidative and Myocardial Stress in Diabetic Ovariectomized Rats. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, 24(4 (84) ), 51-58. SID. https://sid.ir/paper/1127243/en

Vancouver: Copy

Hasanzadeh Dolatabadi Fatemeh, JALALI DEHKORDI KHOSRO, TAGHIAN FARZANEH, HOSEINI SEYED ALI. Effects of Endurance Training and Propolis Against Oxidative and Myocardial Stress in Diabetic Ovariectomized Rats. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2023;24(4 (84) ):51-58. Available from: https://sid.ir/paper/1127243/en

IEEE: Copy

Fatemeh Hasanzadeh Dolatabadi, KHOSRO JALALI DEHKORDI, FARZANEH TAGHIAN, and SEYED ALI HOSEINI, “Effects of Endurance Training and Propolis Against Oxidative and Myocardial Stress in Diabetic Ovariectomized Rats,” JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, vol. 24, no. 4 (84) , pp. 51–58, 2023, [Online]. Available: https://sid.ir/paper/1127243/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops