EVALUATION OF THE EFFECT OF ORAL CLONIDINE IN THE PROPHYLAXIS OF NAUSEA AND VOMITING IN ELECTIVE IN ADULT ORTHOPEDIC SURGERY OF LIMB

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TAHERI AZAM A.; SANJARIPOUR A.; EMAMDADI A.A.F.; ALAVI S.F.; MASHHADI R.

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Journal: Iranian Journal of Surgery Year:2009 | Volume:16 | Issue:4 Page(s): 35-40

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Title

EVALUATION OF THE EFFECT OF ORAL CLONIDINE IN THE PROPHYLAXIS OF NAUSEA AND VOMITING IN ELECTIVE IN ADULT ORTHOPEDIC SURGERY OF LIMB

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Keywords

CLONIDINEQ4

POST OPERATIVE NAUSEA AND VOMITING (PONV)Q4

ORTHOPEDIC SURGERYQ4

Abstract

Introduction & Objective: Post operative nausea and vomiting (PONV) is regarded as important post operative complications that leads to reducing patients satisfaction and other complications such as aspirations pneumonia, wound dehiscence and delay in discharge the patient. Several drugs have been examinated for diminishing this complication during the past few years. In this study we compared the efficacy of oral CLONIDINE in the prevention of PONV in two groups.Materials & Methods: This was a double blind randomized clinical trial performed on 160 patients who were candidate for elective limb ORTHOPEDIC SURGERY at Khatam al-Anbia' (sal) hospital Zahedan, Iran at 2007. The patients were randomly grouped into two 80 member groups. The 1st groups were given 0.1 mg oral CLONIDINE and the 2nd groups were given placebo 45 min before surgery. Then they underwent similar standard anesthetic methods and the follow up was done in recovery room and then in the orthopedic department for maximum of 24 h after surgery. The prevalence of PONV in the two groups was compared through statistical tests.Results: The results of this study in the two groups demonstrated a statistically meaning full difference between the prevalence of PONV in the two groups (P<0.0001). Side effects in both groups were equally rare. Conclusions: Using a low dose of oral CLONIDINE can significantly increase the change of PONY free orthopedic surgeries.

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APA: Copy

TAHERI AZAM, A., SANJARIPOUR, A., EMAMDADI, A.A.F., ALAVI, S.F., & MASHHADI, R.. (2009). EVALUATION OF THE EFFECT OF ORAL CLONIDINE IN THE PROPHYLAXIS OF NAUSEA AND VOMITING IN ELECTIVE IN ADULT ORTHOPEDIC SURGERY OF LIMB . IRANIAN JOURNAL OF SURGERY, 16(4), 35-40. SID. https://sid.ir/paper/112763/en

Vancouver: Copy

TAHERI AZAM A., SANJARIPOUR A., EMAMDADI A.A.F., ALAVI S.F., MASHHADI R.. EVALUATION OF THE EFFECT OF ORAL CLONIDINE IN THE PROPHYLAXIS OF NAUSEA AND VOMITING IN ELECTIVE IN ADULT ORTHOPEDIC SURGERY OF LIMB . IRANIAN JOURNAL OF SURGERY[Internet]. 2009;16(4):35-40. Available from: https://sid.ir/paper/112763/en

IEEE: Copy

A. TAHERI AZAM, A. SANJARIPOUR, A.A.F. EMAMDADI, S.F. ALAVI, and R. MASHHADI, “EVALUATION OF THE EFFECT OF ORAL CLONIDINE IN THE PROPHYLAXIS OF NAUSEA AND VOMITING IN ELECTIVE IN ADULT ORTHOPEDIC SURGERY OF LIMB ,” IRANIAN JOURNAL OF SURGERY, vol. 16, no. 4, pp. 35–40, 2009, [Online]. Available: https://sid.ir/paper/112763/en

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