Estimating the Adverse Reaction Among Iranian Blood Donors: The First National Report

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Taheri Soodejani Moslem; Tabatabaei Seyyed Mohammad; Haghdoost Aliakbar; Amiri Masoud; Baneshi Mohammad Reza; Sedaghat Abbas; Zolala Farzaneh

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Journal Paper

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Journal: Journal of Iranian Medical Council Year:621 | Volume: | Issue: Page(s): 45-51

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Title

Estimating the Adverse Reaction Among Iranian Blood Donors: The First National Report

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Keywords

Blood safetyQ4

HemovigillanceQ4

Adverse effectQ4

Abstract

Background: The aim of this study was to estimate the incidence of reactions caused by blood donations in Iran as well as exploring three potential scenarios of the worst, moderate, and the best situations for adverse reactions among Iranian blood donations by specifying the under-reporting rate. Methods: There are two different designs; first, the ecological study was coducted to estimate the blood donation Adverse effects by using the data registered in the donor vigilance part of Iranian Blood Transfusion Organization (IBTO). Second, the cross-sectional study was conducted to estimate under-reporting in the data. For the cross-sectional study, 2408 donors were selected randomly in three cities. Results: In general, based on the estimations of this study, adverse reactions to blood donation in Iran is 2%(CI 95%, 1.4-2.6%). Local and systemic reactions estimated are 1.7%(CI 95%, 1.2-2.2) and 0.3%(0.1-0.5), respectively. Based on the national report, in general, adverse reactions to blood donation in Iran is 0.5(CI 95% 0.4-0.6). Local and systemic reactions estimated are 0.38%(CI 95% 0.28-0.48) and 0.03%(0.0.02-0.04), respectively. Conclusion: Adverse reactions may vary from region to region in Iran, but in total, there is a lot of under-reporting in the incidence of adverse reactions to blood donation in Iran, most of which are related to local reactions.

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