مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

Investigation of Clinical Significant Utility of LncRNA-LINC02389 in Patients with Esophageal Squamous Cell Carcinoma

Pages

  0-0

Abstract

 Background: The LncRNA LINC02389 Gene/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">LncRNA-LINC02389 Gene is a long non-coding RNA, which has not been an assessed potential role in the pathogenesis of esophageal Squamous Cell Carcinoma (ESCC). Objectives: The purpose of the present survey was to evaluate the LncRNA LINC02389 Gene/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">LncRNA-LINC02389 Gene expression variation in subjects with ESCC. Methods: The present survey was a preliminary investigation performed on seventy-five paired paraffin blocks including tumorous and non-tumorous marginal tissues from subjects with ESCC. After extraction of totalRNAandcDNAsynthesis, the LncRNA LINC02389 Gene/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">LncRNA-LINC02389 Gene expression change was evaluated using quantitative real-time PCR method. Results: Our data declared that the LncRNA LINC02389 Gene/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">LncRNA-LINC02389 Gene was significantly down-regulated in ESCC tissues compared to the marginal tissues (P< 0. 05). In addition, the findingsshoweda significant association betweenthe LncRNA LINC02389 Gene/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">LncRNA-LINC02389 Gene expression change and tumor differentiation grade (P = 0. 003). Conclusions: Our results proposed a possible carcinogenesis character of the LncRNA LINC02389 Gene/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">LncRNA-LINC02389 Gene and may be employed as a prognostic clinical significance in the progression of ESCC.

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  • Cite

    APA: Copy

    Ghasemzadeh, Sahel, & GHORBIAN, SAEID. (2023). Investigation of Clinical Significant Utility of LncRNA-LINC02389 in Patients with Esophageal Squamous Cell Carcinoma. JOURNAL OF KERMANSHAH UNIVERSITY OF MEDICAL SCIENCES (BEHBOOD), 27(2), 0-0. SID. https://sid.ir/paper/1130709/en

    Vancouver: Copy

    Ghasemzadeh Sahel, GHORBIAN SAEID. Investigation of Clinical Significant Utility of LncRNA-LINC02389 in Patients with Esophageal Squamous Cell Carcinoma. JOURNAL OF KERMANSHAH UNIVERSITY OF MEDICAL SCIENCES (BEHBOOD)[Internet]. 2023;27(2):0-0. Available from: https://sid.ir/paper/1130709/en

    IEEE: Copy

    Sahel Ghasemzadeh, and SAEID GHORBIAN, “Investigation of Clinical Significant Utility of LncRNA-LINC02389 in Patients with Esophageal Squamous Cell Carcinoma,” JOURNAL OF KERMANSHAH UNIVERSITY OF MEDICAL SCIENCES (BEHBOOD), vol. 27, no. 2, pp. 0–0, 2023, [Online]. Available: https://sid.ir/paper/1130709/en

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