Evaluation of antimicrobial and antioxidant activities of aqueous and hydroalcoholic extracts of Ferula gummosa Boiss plant gum: An in-vitro study

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Ghasemi Mostafa; Govahi Mostafa; Rajaei Litkohi Hajar

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Birjand University of Medical Sciences Year:2023 | Volume:30 | Issue:3 Page(s): 23-256

Download Full-Text

Persian Verion

View:

Download:

Cites:

Information Journal Paper

Title

Evaluation of antimicrobial and antioxidant activities of aqueous and hydroalcoholic extracts of Ferula gummosa Boiss plant gum: An in-vitro study

Author(s)

Ghasemi Mostafa | Govahi Mostafa | Rajaei Litkohi Hajar | Issue Writer Certificate

Keywords

Antimicrobial activityQ4

Antioxidant activityQ4

Ferula gummosa BoissQ4

Hydroalcoholic extractQ4

Minimum inhibitory concentrationQ4

Abstract

Background and Aims: Due to various antioxidant and antimicrobial compounds, plants are considered valuable sources. Ferula gummosa Boiss plant is one of the most important species of the Apiaceae family and is scattered in the eastern and western regions of Iran. This study aimed to investigate the antioxidant and antimicrobial properties of aqueous and Hydroalcoholic extracts of Ferula gummosa Boiss plant gum. Materials and Methods: The levels of phenolic and flavonoid compounds and the antioxidant capacity (by the iron reduction and 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging methods) were determined in this laboratory study. The Antimicrobial activity of the extracts was evaluated using the disc diffusion method, the Minimum inhibitory concentration (MIC) and minimum bactericidal concentration were determined for some bacteria. Data analysis was performed using a factorial experiment within a completely randomized design, and Duncan's multiple range test was used to compare the means. Results: The highest content of phenolic compounds and flavonoids in methanol extract were (53. 21±2. 43 mg GAE/g dw) and (38. 42±1. 78 mg QE/g dw), respectively. The highest percentage of free radical scavenging and iron reduction power related to the methanolic extract was 96. 43±3. 56% and 1. 963±0. 012 µg/ml, respectively. Antimicrobial activity using the disk diffusion method and the MIC of Bacillus subtilis bacteria in all three extracts showed the most sensitivity compared to other bacteria. Conclusion: The results of this study showed that the methanolic extract of the Ferula gummosa Boiss plant had Antimicrobial activity, antioxidant potential, and higher phenolic and flavonoid content than the ethanolic and aqueous extracts.

Cites

No record.

References