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Information Journal Paper

Title

APPLICATION OF BIOCOMPATIBLE MATERIALS AS OPTICAL DIFFUSERS IN PHOTODYNAMIC THERAPY (PDT)

Pages

  13-17

Keywords

PHOTODYNAMIC THERAPY (PDT)Q3

Abstract

 Background and Objectives: Tumors can be treated by using photodynamic therapy (PDT) technique. In this study, two types of biocompatible DIFFUSERs namely emulsions as liquid and SiO2 powder as solid were used to study the quality of LASER light spatial distribution in gas, liquid and solid media.Material and Methods: The APPLICATOR was used with different number of biocompatible emulsion such as: ginger, coconut, wall nut, hazel nut, olive, bitter and sweat almond, neutralipid and phospholipid as optical DIFFUSERs. The second type of DIFFUSERs (solid) was made of SiO2 powder in different geometrical shapes. The uniformity of angular distribution of LASER power and intensity emitted from the emulsion containing silicon rubber balloon and solid DIFFUSERs were measured at different diameters. Also, lamb meat and chicken breast were used as dark and light samples.Results: Among the pure oils and emulsions used in these experiments, the pure phospholipid and hazel nut were found as the best and worst liquid DIFFUSERs respectively.Also, the results showed that the spatial distribution uniformity was improved by increasing the balloon diameter. Finally, in the case of solid DIFFUSERs "castted" technique indicated a better mechanical strength as well as diffusing behavior with respect to "pulled” technique.Conclusions: Phospholipids emulsion showed an excellent scattering properties and uniformity of spatial distribution was improved at higher balloon diameters. The geometrical shape as well as mechanical and thermal properties of solid DIFFUSER such as SiO2 fiber is an important deciding parameter in a successful PDT operation.

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    APA: Copy

    ETRATI KHOSROU SHAHI, S.M., & ARJMAND, M.R.. (2005). APPLICATION OF BIOCOMPATIBLE MATERIALS AS OPTICAL DIFFUSERS IN PHOTODYNAMIC THERAPY (PDT). LASER IN MEDICINE, 3(4 (22)), 13-17. SID. https://sid.ir/paper/113464/en

    Vancouver: Copy

    ETRATI KHOSROU SHAHI S.M., ARJMAND M.R.. APPLICATION OF BIOCOMPATIBLE MATERIALS AS OPTICAL DIFFUSERS IN PHOTODYNAMIC THERAPY (PDT). LASER IN MEDICINE[Internet]. 2005;3(4 (22)):13-17. Available from: https://sid.ir/paper/113464/en

    IEEE: Copy

    S.M. ETRATI KHOSROU SHAHI, and M.R. ARJMAND, “APPLICATION OF BIOCOMPATIBLE MATERIALS AS OPTICAL DIFFUSERS IN PHOTODYNAMIC THERAPY (PDT),” LASER IN MEDICINE, vol. 3, no. 4 (22), pp. 13–17, 2005, [Online]. Available: https://sid.ir/paper/113464/en

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