LOW LEVEL LASER THERAPY IN TREATMENT OF DIABETIC FOOT ULCERS: DOUBLE BLIND CONTROLLED CLINICAL TRIAL

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ATAEI FASHTAMI L.; ESMAEILI JAVID GH.R.; KAVIANI AHMAD; ARDESHIR LARIJANI MOHAMMAD BAGHER; RAZAVI LALEH; SALAMI MALIEH; FATEH M.; SEYYED FATEMI S.M.; MORTAZAVI S.M.J.

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Journal: Lasers in Medicine Year:2009 | Volume:5 | Issue:3-4 (29-30) Page(s): 6-11

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Title

LOW LEVEL LASER THERAPY IN TREATMENT OF DIABETIC FOOT ULCERS: DOUBLE BLIND CONTROLLED CLINICAL TRIAL

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Keywords

DIABETI0 FOOT ULCERQ4

DOUBLE BLIND CLINICAL TRIALQ3

LOW LEVEL LASER IRRADIATIONQ4

GAALASQ4

WOUND AREAQ4

Abstract

Background and Objectives: Diabetic foot problem due to angiopathy and neuropaty account for 50% of all nontraumatic amputations and constitute a significant economic burden to society. LOW LEVEL LASER IRRADIATION (I-III) has been shown to induce wound healing in conditions of reduced microcirculation. We investigated the influence of I-III on wound healing by measure the lesion.Materials and Methods: Sixteen patients with grade I-III diabetic foot for at least three months before this study were included in this double blind randomized clinical trial. Patients received placebo (n=6) or laser irradiation (n=10) (GaAlAs/ BTL 685 nm, fluence: 5 J/cm2) over the lesions. Reduction in lesion area was measured and compared between laser and placebo groups.Results: There were no statistical significant differences in baseline characteristics patients and lesions between laser and placebo groups. Reduction average of lesion areas in laser group was 93.2% vs. with 32.9% in placebo group. Healing rate in laser group was 70% in comparison to placebo group (33.3%) during 16 weeks follow-up (p=0.072).Conclusion: The data from this first randomized double- blind placebo- controlled clinical trial demonstrates an increase in healing of diabetic foot lesions.

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زخم پای دیابتی: تشخیص و درمان

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APA: Copy

ATAEI FASHTAMI, L., ESMAEILI JAVID, GH.R., KAVIANI, AHMAD, ARDESHIR LARIJANI, MOHAMMAD BAGHER, RAZAVI, LALEH, SALAMI, MALIEH, FATEH, M., SEYYED FATEMI, S.M., & MORTAZAVI, S.M.J.. (2009). LOW LEVEL LASER THERAPY IN TREATMENT OF DIABETIC FOOT ULCERS: DOUBLE BLIND CONTROLLED CLINICAL TRIAL. LASER IN MEDICINE, 5(3-4 (29-30)), 6-11. SID. https://sid.ir/paper/113525/en

Vancouver: Copy

ATAEI FASHTAMI L., ESMAEILI JAVID GH.R., KAVIANI AHMAD, ARDESHIR LARIJANI MOHAMMAD BAGHER, RAZAVI LALEH, SALAMI MALIEH, FATEH M., SEYYED FATEMI S.M., MORTAZAVI S.M.J.. LOW LEVEL LASER THERAPY IN TREATMENT OF DIABETIC FOOT ULCERS: DOUBLE BLIND CONTROLLED CLINICAL TRIAL. LASER IN MEDICINE[Internet]. 2009;5(3-4 (29-30)):6-11. Available from: https://sid.ir/paper/113525/en

IEEE: Copy

L. ATAEI FASHTAMI, GH.R. ESMAEILI JAVID, AHMAD KAVIANI, MOHAMMAD BAGHER ARDESHIR LARIJANI, LALEH RAZAVI, MALIEH SALAMI, M. FATEH, S.M. SEYYED FATEMI, and S.M.J. MORTAZAVI, “LOW LEVEL LASER THERAPY IN TREATMENT OF DIABETIC FOOT ULCERS: DOUBLE BLIND CONTROLLED CLINICAL TRIAL,” LASER IN MEDICINE, vol. 5, no. 3-4 (29-30), pp. 6–11, 2009, [Online]. Available: https://sid.ir/paper/113525/en

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