EVALUATION OF EFFICACY OF PHOTODYNAMIC THERAPY IN BASAL CELL CARCINOMA WITH 6 MONTHS FOLLOW-UP

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TEHRANCHINIA Z.; RAHIMI H.; RAHIMI A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Lasers in Medicine Year:2009 | Volume:6 | Issue:2 (32) Page(s): 6-12

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Title

EVALUATION OF EFFICACY OF PHOTODYNAMIC THERAPY IN BASAL CELL CARCINOMA WITH 6 MONTHS FOLLOW-UP

Author(s)

TEHRANCHINIA Z. | RAHIMI H. | RAHIMI A. | Issue Writer Certificate

Keywords

BASAL CELL CARCINOMAQ4

PHOTODYNAMIC THERAPYQ2

PHOTO CHEMOTHERAPYQ4

Abstract

Background and objective: BASAL CELL CARCINOMA (BCC) is the most common skin cancer. PHOTODYNAMIC THERAPY (PDT) -as a novel, non-invasive therapeutic approach- may be considered a valuable strategy. This study was designed with the aim of the evaluation of efficacy of PDT in treatment of BCC.Methods: This was a clinical trial which was done on 28 patients with BCC. Patients were treated with ALAPDT for 1-6 sessions monthly and evaluated for clinical response, cosmetic results and probable side effects.Results: From 28 lesions 82.1% had some response to PDT (32.1% complete response and 50% partial response). Cosmetic result was excellent or good in 77.5% of cases. In 92.8% of cases no or mild side effect was observed. Patients with positive history of radiotherapy had less response (p<0.05). No significant relation was found between patient's age or sex, localization, diameter and type of BCC with clinical response. At 6 months, none of the lesions had recurrence.Conclusion: PDT would be a good therapeutic option in treatment of BCC -especially superficial type- with high efficacy and low side effect.

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APA: Copy

TEHRANCHINIA, Z., RAHIMI, H., & RAHIMI, A.. (2009). EVALUATION OF EFFICACY OF PHOTODYNAMIC THERAPY IN BASAL CELL CARCINOMA WITH 6 MONTHS FOLLOW-UP. LASER IN MEDICINE, 6(2 (32)), 6-12. SID. https://sid.ir/paper/113549/en

Vancouver: Copy

TEHRANCHINIA Z., RAHIMI H., RAHIMI A.. EVALUATION OF EFFICACY OF PHOTODYNAMIC THERAPY IN BASAL CELL CARCINOMA WITH 6 MONTHS FOLLOW-UP. LASER IN MEDICINE[Internet]. 2009;6(2 (32)):6-12. Available from: https://sid.ir/paper/113549/en

IEEE: Copy

Z. TEHRANCHINIA, H. RAHIMI, and A. RAHIMI, “EVALUATION OF EFFICACY OF PHOTODYNAMIC THERAPY IN BASAL CELL CARCINOMA WITH 6 MONTHS FOLLOW-UP,” LASER IN MEDICINE, vol. 6, no. 2 (32), pp. 6–12, 2009, [Online]. Available: https://sid.ir/paper/113549/en

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