Synthesis, Spectral, Cancer Inhibitory Activity and Antimicrobial Studies of Cobalt(II) and Nickel(II) Metal Complexes Containing Azo Derived from 2-Amino Benzimidazole

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Hasan Neda; Hasan Shallal Muhammed Abdel; A. Mubarak Hayfaa; M.Karhib Mustafa; S. Naje Ahmed

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ISSN: 2588-4824

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Paper Information

Journal: Journal of Medicinal and Chemical Sciences Year:2023 | Volume:6 | Issue:8 Page(s): 1885-1896

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Title

Synthesis, Spectral, Cancer Inhibitory Activity and Antimicrobial Studies of Cobalt(II) and Nickel(II) Metal Complexes Containing Azo Derived from 2-Amino Benzimidazole

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Synthesis Imidazolylazo dye Spectrum studies Breast cancer (MCFQ4

7)Q4

Abstract

The production of the tridentate Azo ligand 2-[2/-(benzimidazolyl)azo]-4-bromo-6-chloro phenol (BIABrClP) complexes using Co(III) and Ni(II) is discussed in this article. Spectral methods including 1H-NMR, UV-Vis, FT-IR, magnetic moment measurements, molar conductance, and elemental analysis were used to thoroughly explore the coordination mode of azo ligand containing NNO donor atoms with metal ions. The octahedral geometry for the synthesized Ni(II) and Co(III) complexes was suggested from the analytical and spectral studies. According to in vitro assays for antibacterial activity, the majority of produced compounds exhibit good action against a variety of microorganisms, including Candida albicans, Staphylococcus aureus, and Escherichia coli.

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