Seroloprevalence of Hepatits G Virus (HGV) in Beta-Thalassemia Patients Jahrom-Iran, 1399

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SHAKERI MASIHOLLAH; Razaghzadeghan Hanieh; RAHMANIAN KARAMATOLLAH; Sotoodeh Jahromi Fatemeh; SOTOODEH JAHROMI ABDOLREZA

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Journal: Pars Journal of Medical Sciences Year:2021 | Volume:19 | Issue:3 Page(s): 39-44

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Title

Seroloprevalence of Hepatits G Virus (HGV) in Beta-Thalassemia Patients Jahrom-Iran, 1399

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Keywords

Seroprevalence

Hepatitis G Virus (HGV)

Sero-Prevalence

Thalassemia

Iran

Abstract

Introduction: People who have multiple transfusions, such as Beta-Thalassemia patients, are at risk for the hepatitis G virus (HGV) infection. The aim of the study was the determination of serological prevalence of HGV and its associated factors in beta-Thalassemia major patients in Jahrom-Iran. Material and Methods: This cross-sectional study, was done on 91 beta-Thalassemia patients referring to the Thalassemia center, Jahrom-Iran, 2021. Blood samples were collected from the patients and anti-HGV antibodies were evaluated by ELISA methods. Serum levels of ALT, AST, ALP and demographic data were extracted from patients' medical records. Descriptive analysis, X2, and T-test were used for statistical analyses by SPSS-16. Results: The prevalence anti-HGV IgG and IgM were 18. 7 % and 5. 5 %, respectively. There were significant relationships between the frequencies of anti-HGV antibodies and serum level of ALT, ASL, ALP and also with the history time of transfusion (P<0. 05). But, there were no significant relationships between the frequencies of anti-HGV antibodies with patients' sex and the mean of age (P>0. 05). Conclusions: HGV is one of the etiologic factors of hepatitis in Thalassemia patients in Jahrom. Further comprehensive and molecular-based studies are recommended to explore the prevalence of HGV and its role in hepatitis Thalassemia patients.

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APA: Copy

SHAKERI, MASIHOLLAH, Razaghzadeghan, Hanieh, RAHMANIAN, KARAMATOLLAH, Sotoodeh Jahromi, Fatemeh, & SOTOODEH JAHROMI, ABDOLREZA. (2021). Seroloprevalence of Hepatits G Virus (HGV) in Beta-Thalassemia Patients Jahrom-Iran, 1399. PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL), 19(3 ), 39-44. SID. https://sid.ir/paper/1142743/en

Vancouver: Copy

SHAKERI MASIHOLLAH, Razaghzadeghan Hanieh, RAHMANIAN KARAMATOLLAH, Sotoodeh Jahromi Fatemeh, SOTOODEH JAHROMI ABDOLREZA. Seroloprevalence of Hepatits G Virus (HGV) in Beta-Thalassemia Patients Jahrom-Iran, 1399. PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL)[Internet]. 2021;19(3 ):39-44. Available from: https://sid.ir/paper/1142743/en

IEEE: Copy

MASIHOLLAH SHAKERI, Hanieh Razaghzadeghan, KARAMATOLLAH RAHMANIAN, Fatemeh Sotoodeh Jahromi, and ABDOLREZA SOTOODEH JAHROMI, “Seroloprevalence of Hepatits G Virus (HGV) in Beta-Thalassemia Patients Jahrom-Iran, 1399,” PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL), vol. 19, no. 3 , pp. 39–44, 2021, [Online]. Available: https://sid.ir/paper/1142743/en

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