Frequency of Stress Hyperglycemia and Its Effect on Disease Outcome in COVID-19 Patients Referred to the Imam Khomeini Medical Education Center in Sari

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Mosayyebi Maryam; Kashi Zahra; Bahar Adele; Mohammadpour Reza Ali

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Journal Paper

Paper Information

Journal: Journal of Mazandaran University of Medical Sciences Year:2023 | Volume:33 | Issue:228 Page(s): 57-67

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Information Journal Paper

Title

Frequency of Stress Hyperglycemia and Its Effect on Disease Outcome in COVID-19 Patients Referred to the Imam Khomeini Medical Education Center in Sari

Author(s)

Mosayyebi Maryam | Kashi Zahra | Bahar Adele | Mohammadpour Reza Ali | Issue Writer Certificate

Keywords

stress hyperglycemiaQ4

COVID-19Q4

hyperglycemiaQ4

disease severityQ4

clinical outcomeQ4

Abstract

Background and purpose: stress hyperglycemia is a neuroendocrine physiological response to medical stress, hyperglycemic stress increases the risk of mortality and morbidity in ill patients. This study aimed to investigate the frequency of hyperglycemic stress and its related factors, as well as the relationship between hyperglycemia and the severity and clinical outcomes of hospitalized patients with COVID-19. Materials and methods: This cross-sectional study was conducted in Imam Khomeini Hospital in Sari in 2019. The patients were diagnosed based on clinical symptoms, CBC, CRP, ESR tests, RT-PCR test, and CT scan of the lungs and were hospitalized in the Covid ward. Data analysis was performed using SPSS Software. Results: 312 COVID-19 patients were investigated, and 22 (7. 1%) suffered from hyperglycemic stress. Hyperglycemic stress patients had more mortality, hospitalization in ICU, respiratory ventilation, and length of hospital stay compared to the normoglycemic subjects, but only in terms of mortality, there was a statistically significant difference between the two groups (P=0. 46) Conclusion: Considering the effect of hyperglycemia on the outcome of the disease and the death rate in ill and hospitalized patients compared to patients with normal blood sugar, it shows the importance of timely diagnosis and proper control of blood sugar in these patients.

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