مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

Vaccine Adjuvants: Selection Criteria, Mechanism of Action Associated with Immune Responses and Future Directions

Pages

  1-15

Abstract

 The most effective method to minimize the prevalence of infectious diseases is vaccination. Vaccines enhance immunity and provide protection against different kinds of infections. Subunit Vaccines are safe and less toxic, but due to their lower immunogenicity, they need Adjuvants to boost the Immune system. Adjuvants are small particles/molecules integrated into a Vaccine to enhance the Immunogenic feedback of antigens. They play a significant role to enhance the potency and efficiency of Vaccines. There are several types of Adjuvants with different mechanisms of action,therefore, improved knowledge of their immunogenicity will help develop a new generation of Adjuvants. Many trials have been designed using different kinds of Vaccine Adjuvants to examine their safety and efficacy, but in practice, only a few have entered in animal and human clinical trials. However, for the development of safe and effective Vaccines, it is important to have adequate knowledge of the side effects and toxicity of different Adjuvants. The current review discussed the Adjuvants which are available for producing modern Vaccines as well as some new classes of Adjuvants in clinical trials.

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    • Cite

    APA: Copy

    Habib, Arslan, Anjum, Khalid Mahmood, Iqbal, Riffat, Jaffar, Ghulam, Ashraf, Zeeshan, Khalid, Malik ShahZaib, Taj, Muhammad Usman, Zainab, Syeda Wafa, Umair, Muhammad, Zohaib, Muhammad, & Khalid, Tabinda. (2023). Vaccine Adjuvants: Selection Criteria, Mechanism of Action Associated with Immune Responses and Future Directions. IRANIAN JOURNAL OF IMMUNOLOGY (IJI), 20(1), 1-15. SID. https://sid.ir/paper/1145435/en

    Vancouver: Copy

    Habib Arslan, Anjum Khalid Mahmood, Iqbal Riffat, Jaffar Ghulam, Ashraf Zeeshan, Khalid Malik ShahZaib, Taj Muhammad Usman, Zainab Syeda Wafa, Umair Muhammad, Zohaib Muhammad, Khalid Tabinda. Vaccine Adjuvants: Selection Criteria, Mechanism of Action Associated with Immune Responses and Future Directions. IRANIAN JOURNAL OF IMMUNOLOGY (IJI)[Internet]. 2023;20(1):1-15. Available from: https://sid.ir/paper/1145435/en

    IEEE: Copy

    Arslan Habib, Khalid Mahmood Anjum, Riffat Iqbal, Ghulam Jaffar, Zeeshan Ashraf, Malik ShahZaib Khalid, Muhammad Usman Taj, Syeda Wafa Zainab, Muhammad Umair, Muhammad Zohaib, and Tabinda Khalid, “Vaccine Adjuvants: Selection Criteria, Mechanism of Action Associated with Immune Responses and Future Directions,” IRANIAN JOURNAL OF IMMUNOLOGY (IJI), vol. 20, no. 1, pp. 1–15, 2023, [Online]. Available: https://sid.ir/paper/1145435/en

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