Relationship Between rs1800896 and rs1465618 Polymorphisms in Prostate Adenocarcinoma in the Iranian Population

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Tolue Golnoosh; Angaji Seyed Abdolhamid; Beikzadeh Behnaz; Alibeik Hengameh; Roudi Raheleh; Narouie Behzad

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Gorgan University of Medical Sciences Year:2023 | Volume: | Issue: Page(s): 43-49

Download Full-Text

Persian Verion

View:

Download:

Cites:

Information Journal Paper

Title

Relationship Between rs1800896 and rs1465618 Polymorphisms in Prostate Adenocarcinoma in the Iranian Population

Author(s)

Keywords

Prostate [MeSH]Q4

Adenocarcinoma [MeSH]Q4

Interleukin-10 [MeSH]Q4

Single Nucleotide Polymorphisms (SNP) [MeSH]Q4

Iran [MeSH]Q4

Abstract

Background and Objective: Prostate cancer is a malignancy affecting men. Identifying risk factors for prostate cancer is crucial for the potential development of interventions and expanding our biological understanding of this disease. The present study investigated the association of rs1800896 and rs1800896 with prostate adenocarcinoma. Methods: This case-control study was conducted on 176 men, including 78 patients with prostate adenocarcinoma (case group) and 98 men with benign prostatic hyperplasia (control group), who visited the Labafinejad Educational and Treatment Center in Tehran, Iran. Genotyping was performed using the Tetra ARMS-PCR (amplification refractory mutation system-polymerase chain reaction) method. Results: There was no statistically significant difference between the case and control groups in the genotype frequency of rs1800896 and rs1465618. However, the rs1800896 polymorphism was associated with PSA levels less than or equal to 4 ng/mL (P<0. 05). Significant associations were found between rs1800896 and rs1465618 polymorphisms and clinical features, such as perineural invasion (P<0. 05). Conclusion: The rs1800896 and rs1465618 polymorphisms were not associated with the risk of prostate adenocarcinoma.

Cites

No record.

References