Effect of Saffron Supplementation and Aerobic Training on Interleukin-6, Interleukin-10 and L-Concentrations in Outpatients with Coronavirus

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halalkhor fateme; poorrahim ameneh; Siahkouhian Marefat

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Journal Paper

Paper Information

Journal: Journal of Arak University Medical Sciences Year:2023 | Volume:26 | Issue:5 Page(s): 1-8

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Information Journal Paper

Title

Effect of Saffron Supplementation and Aerobic Training on Interleukin-6, Interleukin-10 and L-Concentrations in Outpatients with Coronavirus

Author(s)

halalkhor fateme | poorrahim ameneh | Siahkouhian Marefat | Issue Writer Certificate

Keywords

exerciseQ4

saffronQ4

coronavirusQ4

interleukinQ4

alcysteineQ4

Abstract

2Background and purpose: Anti-cytokine considerations in covid-19 patients can play a significant role in preventing death, therefore, physical activity by reducing risk factors, as well as saffron with anti-inflammatory and antioxidant properties, are considered as anti-cytokine solutions. Therefore, the purpose of this research is to investigate the effect of saffron supplementation and endurance training on the concentration of interleukin-6, interleukin-10 and cysteine in outpatients with coronavirus. Materials and methods: The statistical population of this research is outpatients with coronavirus, 36 of whom were randomly selected. Cytokines and cysteine were measured using a special kit and ELISA method. The research hypotheses were checked using SPSS software at a significance level of P<0.05 using ANOVA test with repeated measurements with between-group factor. Results: The results showed that endurance activity and saffron supplementation caused a significant decrease in IL-6 levels and the ratio of interleukin 6 to interleukin 10 (P≥0.05). Also, endurance activity along with saffron supplementation caused a significant increase in serum L-cysteine concentration (P=0.035). The results showed that there is no interaction effect between the measurement stages and the group, as well as intra-group and inter-group differences in interleukin-10 variables (P=0.511). Conclusion: The levels of IL-6 and IL-10 decrease due to saffron supplementation and endurance training, and the amount of cysteine increases, which helps the recovery of covid-19 patients.

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