A Review of Advances in the Development of Bioresorbable Nano Stents: Part (II)

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Mohamed Sikkander Abdul Razak; Yadav Hazarathaiah; Meena Manoharan; Lakshmi V. Vidya

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Journal Paper

Paper Information

Journal: JOURNAL OF CHEMICAL REVIEWS Year:2024 | Volume:6 | Issue:3 Page(s): 304-330

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Information Journal Paper

Title

A Review of Advances in the Development of Bioresorbable Nano Stents: Part (II)

Author(s)

Mohamed Sikkander Abdul Razak | Yadav Hazarathaiah | Meena Manoharan | Lakshmi V. Vidya | Issue Writer Certificate

Keywords

Critical healing phase

Thrombosis persist

Biocompatibility

Drug Delivery

Abstract

Bioresorbable nano stents represent a revolutionary advancement in the field of interventional cardiology, offering a novel approach to address the challenges associated with traditional stent technologies. These innovative devices are designed to provide temporary structural support to blood vessels during the critical healing phase following interventions, such as angioplasty. The key feature of bioresorbable nano stents lies in their ability to gradually degrade over time, aligning with the natural healing processes of the body. Nanotechnology plays a pivotal role in the development of bioresorbable nano stents, allowing for precise control over material properties, degradation kinetics, and biocompatibility. The customization afforded by nanomaterials enables tailoring stent characteristics to match the specific needs of individual patients and diverse clinical scenarios. This level of customization contributes to enhanced safety, reduced risk of complications, and improved patient outcomes. The controlled degradation of bioresorbable nano stents eliminates the long-term presence of foreign materials in the body, potentially mitigating late complications associated with permanent stents, such as in-stent restenosis and thrombosis. This abstract explores the potential benefits of bioresorbable nano stents, including their role in minimizing inflammatory responses and adverse reactions. In addition, the integration of nanotechnology enables the incorporation of imaging agents, antimicrobial coatings, and other functionalities, further expanding the capabilities of these innovative medical devices. The dynamic nature of nanomedicine, coupled with interdisciplinary collaboration, continues to drive advancements in bioresorbable nano stents, positioning them as a transformative technology in the landscape of cardiovascular interventions.

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