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Title

SERUM ANTIOXIDATIVE AND OXIDATIVE STRESS BIOMARKERS RESPONSE TO SHORT-TERM CAFFEINE (1,3,7-TRIMETHYLXANTHINE) SUPPLEMENTATION AND ONE SESSION OF AEROBIC EXERCISE IN ACTIVE MALES

Pages

  55-63

Abstract

 Background and Objectives: Because of its stimulant effects, CAFFEINE has long enjoyed wide acceptance among the various strata of the society. This study aims to determine the effect of short-term CAFFEINE supplementation on some of antioxidant (GPx and SOD) and lipid peroxidation (MDA) indices responses in serum active men after one-session AEROBIC EXERCISE.Materials and Methods: Twenty active males (mean age 25±3 years, body fat 13±2% and VO2max 52±4 ml/kg-1/min) into a experimental, randomized and double-blind design were divided in two homogeneous supplement and placebo groups (5 mg.kg-1.day CAFFEINE or Dextrose). After 14 days of supplementation, all subjects were participated in the AEROBIC EXERCISE protocol (running on the treadmill at the -15% incline for 30 min with 65% VO2max). Blood samples were taken at three phases (baseline, after supplementation period and immediately after the exercise). Data were analyzed by repeated measure ANOVA, Bonferroni and independent t-test at a£0.05.Results: The results showed that the 14-days CAFFEINE intake had significant effect on the basal ant ioxidative enzymes (GPx and SOD) capacity (P£0.05). Moreover, 30 min AEROBIC EXERCISE significantly reduced ant ioxidative power (P£0.05) and significantly increased in the OXIDATIVE STRESS markers (MDA) (P£0.05). However, increased levels of OXIDATIVE STRESS markers in the placebo group were significantly more than in the CAFFEINE group (P£0.05).Conclusion: Our results suggest that the increased basal ant ioxidative capacity (GPx and SOD) following CAFFEINE supplementation can decrease the undesirable alterations of exercise-induced oxidative damage (MDA) in active males.

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    APA: Copy

    NIKKHEDAR, J., ZARGHAMI KHAMENEH, A., MALEKIRAD, A.A., & HOSSEINI HOORIPASAND, E.. (2016). SERUM ANTIOXIDATIVE AND OXIDATIVE STRESS BIOMARKERS RESPONSE TO SHORT-TERM CAFFEINE (1,3,7-TRIMETHYLXANTHINE) SUPPLEMENTATION AND ONE SESSION OF AEROBIC EXERCISE IN ACTIVE MALES. JOURNAL OF NUTRITION SCIENCES & FOOD TECHNOLOGY, 11(2), 55-63. SID. https://sid.ir/paper/121187/en

    Vancouver: Copy

    NIKKHEDAR J., ZARGHAMI KHAMENEH A., MALEKIRAD A.A., HOSSEINI HOORIPASAND E.. SERUM ANTIOXIDATIVE AND OXIDATIVE STRESS BIOMARKERS RESPONSE TO SHORT-TERM CAFFEINE (1,3,7-TRIMETHYLXANTHINE) SUPPLEMENTATION AND ONE SESSION OF AEROBIC EXERCISE IN ACTIVE MALES. JOURNAL OF NUTRITION SCIENCES & FOOD TECHNOLOGY[Internet]. 2016;11(2):55-63. Available from: https://sid.ir/paper/121187/en

    IEEE: Copy

    J. NIKKHEDAR, A. ZARGHAMI KHAMENEH, A.A. MALEKIRAD, and E. HOSSEINI HOORIPASAND, “SERUM ANTIOXIDATIVE AND OXIDATIVE STRESS BIOMARKERS RESPONSE TO SHORT-TERM CAFFEINE (1,3,7-TRIMETHYLXANTHINE) SUPPLEMENTATION AND ONE SESSION OF AEROBIC EXERCISE IN ACTIVE MALES,” JOURNAL OF NUTRITION SCIENCES & FOOD TECHNOLOGY, vol. 11, no. 2, pp. 55–63, 2016, [Online]. Available: https://sid.ir/paper/121187/en

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