MYOCARDIAL ISCHEMIA IN A PATIENT WITH SICKLE CELL βO THALASSEMIA AND ITS RESPONSE TO YDROXYUREA: A CASE REPORT

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MOULAVI M.A.; NADERI ALI; ZANDIAN KH.M.; PEDRAM MOHAMMAD; SAADATI S.M.

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Title

MYOCARDIAL ISCHEMIA IN A PATIENT WITH SICKLE CELL βO THALASSEMIA AND ITS RESPONSE TO YDROXYUREA: A CASE REPORT

Author(s)

Keywords

SICKLE CELL β THALASSEMIAQ3

HYDROXYUREAQ3

MYOCARDIAL INFARCTIONQ3

Abstract

Sickle cell Patients with either homozygous or heterozygous forms of bo-sickle cell thalassemia are at risk of developing cardiac problems, including the occurrence of sudden unexpected death. Sudden death can arise from significant morphological abnormalities in the cardiac conduction system. However, MYOCARDIAL INFARCTION is a rare occurrence in young adults with sickle cell disease and may be attributable, in most cases, to acute micro-vascular occlusion of small vessels.In this report, we present an Abadanian, 22 year-old young adult man every Arab ethnicity, who's disease started six years ago with bone pains, and was under six-monthly blood transfusion for control of anemia. Recently he was admitted for bone and chest pain. Perfusion thaliam-scan suggested a myocardial ischemia for which he was treated with hydroxylurea.In view of the fact that the hallmark of sickle cell disease is micro-vascular occlusion, treatment with HYDROXYUREA not only improved bone and chest pain but also, in this case, caused the disappearance of his myocardial ischemia, raising in Hb-F level and reduced the rate of blood transfusion.

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APA: Copy

MOULAVI, M.A., NADERI, ALI, ZANDIAN, KH.M., PEDRAM, MOHAMMAD, & SAADATI, S.M.. (2008). MYOCARDIAL ISCHEMIA IN A PATIENT WITH SICKLE CELL β^O THALASSEMIA AND ITS RESPONSE TO YDROXYUREA: A CASE REPORT. JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL, 7(2 (57)), 290-294. SID. https://sid.ir/paper/12386/en

Vancouver: Copy

MOULAVI M.A., NADERI ALI, ZANDIAN KH.M., PEDRAM MOHAMMAD, SAADATI S.M.. MYOCARDIAL ISCHEMIA IN A PATIENT WITH SICKLE CELL β^O THALASSEMIA AND ITS RESPONSE TO YDROXYUREA: A CASE REPORT. JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL[Internet]. 2008;7(2 (57)):290-294. Available from: https://sid.ir/paper/12386/en

IEEE: Copy

M.A. MOULAVI, ALI NADERI, KH.M. ZANDIAN, MOHAMMAD PEDRAM, and S.M. SAADATI, “MYOCARDIAL ISCHEMIA IN A PATIENT WITH SICKLE CELL β^O THALASSEMIA AND ITS RESPONSE TO YDROXYUREA: A CASE REPORT,” JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL, vol. 7, no. 2 (57), pp. 290–294, 2008, [Online]. Available: https://sid.ir/paper/12386/en

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